Saltar al contenido
MilliporeSigma
Todas las fotos(1)

Key Documents

View All Documentation

SMB01354

Sigma-Aldrich

Losartan carboxylic acid

≥95% (HPLC)

Sinónimos:

EXP3174, 2-Butyl-4-chloro-1-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylic acid, E-3174, EXP 3174, EXP-3174

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
Todas las fotos(1)

About This Item

Fórmula empírica (notación de Hill):
C22H21ClN6O2
Número de CAS:
124750-92-1
Peso molecular:
436.89
MDL number:
MFCD00871928
UNSPSC Code:
12352106
NACRES:
NA.21

Quality Level

100

assay

≥95% (HPLC)

form

solid

shipped in

wet ice

InChI

1S/C22H21ClN6O2/c1-2-3-8-18-24-20(23)19(22(30)31)29(18)13-14-9-11-15(12-10-14)16-6-4-5-7-17(16)21-25-27-28-26-21/h4-7,9-12H,2-3,8,13H2,1H3,(H,30,31)(H,25,26,27,28)

InChI key

ZEUXAIYYDDCIRX-UHFFFAOYSA-N

¿Está buscando productos similares? Visita Guía de comparación de productos

General description

Losartan Carboxylic Acid (E-3174) is an active carboxylic acid metabolite of Losartan. Losartan Carboxylic Acid is a potent and selective angiotensin II receptor type 1 (AT1) antagonist.

Application

Metabolomics research

Other Notes

For additional information on our range of Biochemicals, please complete this form.

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Danger

Hazard Classifications

Lact. - Repr. 1B - Skin Sens. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Elija entre una de las versiones más recientes:

Certificados de análisis (COA)

Lot/Batch Number

Lo sentimos, en este momento no disponemos de COAs para este producto en línea.

Si necesita más asistencia, póngase en contacto con Atención al cliente

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Eleni Karatza et al.
Basic & clinical pharmacology & toxicology, 126(3), 193-202 (2019-09-13)
Losartan presents multiple peaks in the concentration-time profile. This characteristic can be attributed to gastric emptying, which is known to significantly affect the disposition of highly soluble and permeable compounds. The aim of this study was to develop a population
A Gromotowicz-Poplawska et al.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 70(3) (2019-10-01)
The aim of the study was to evaluate the effect of an active metabolite of losartan - EXP3174 - on a performed venous thrombus in hypertensive rat. The contribution of coagulation and fibrinolytic systems as well as platelets in the
L L Chang et al.
Journal of medicinal chemistry, 36(17), 2558-2568 (1993-08-20)
A series of 2,4-dihydro-2,4,5-trisubstituted-3H-1,2,4-triazol-3-ones was prepared via several synthetic routes and evaluated as AII receptor antagonists in vitro and in vivo. The preferred compounds contained a [2'-(5-tetrazolyl)biphenyl-4-yl]methyl side chain at N4 and an n-butyl group at C5. A number of

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico