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MilliporeSigma

PVP40

Sigma-Aldrich

Polyvinylpyrrolidone

average mol wt 40,000

Sinónimos:

PVP, Polyvidone, Povidone

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About This Item

Fórmula lineal:
(C6H9NO)n
Número de CAS:
MDL number:
UNSPSC Code:
12161700
PubChem Substance ID:
NACRES:
NA.25

biological source

synthetic (oragnic)

Quality Level

form

powder

mol wt

average mol wt 40,000

impurities

<5.0% water (Karl Fischer)

viscosity number

29-32(lit.)

solubility

water: 100 mg/mL, clear, colorless to light yellow

application(s)

agriculture

SMILES string

C=CN1CCCC1=O

InChI

1S/C6H9NO/c1-2-7-5-3-4-6(7)8/h2H,1,3-5H2

InChI key

WHNWPMSKXPGLAX-UHFFFAOYSA-N

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General description

Polyvinylpyrrolidone (PVP) can form complexes with phenolics and alkaloids. The complex formation allows removal of phenolics and alkaloids from plant samples, thereby inhibiting any modification of proteins by them and any hindrance they may cause in spectrophotometric determinations of protein content. PVP might also enhances the stability of enzymes.
Polyvinylpyrrolidone (PVP), a multifunctional synthetic polymer, finds utility in life science and biochemical research. This water-soluble polymer is versatile, serving as a stabilizing agent, emulsifier, suspending agent, solubilizing agent, protective colloid, and complexing agent. Its protective colloid properties are particularly valuable in stabilizing proteins, enzymes, and other biological substances.

Application

Polyvinylpyrrolidone has been used in the purification of glutamine synthetases from plant samples. It has been used to block the PVDF (polyvinylidene difluoride) membrane and to avoid nonspecific binding.

Features and Benefits

  • Highly versatile surfactant for your life science and biochemical research
  • Excellent Solubilizing agent and Complexing agent

Other Notes

Polyvinylpyrrolidone is a component of Denhardt′s Solution and is included at a concentration of 1% (w/v) in the standard 50X stock solution.
For additional information on our range of Biochemicals, please complete this form.

Comparable product

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Visite la Librería de documentos

Glutamine Synthetases of Higher Plants : Evidence for a Specific Isoform Content Related to Their Possible Physiological Role and Their Compartmentation within the Leaf.
McNally SF et al.
Plant Physiology, 72, 22-22 (1983)
Angiotensin II inhibits insulin signaling in aortic smooth muscle cells at multiple levels. A potential role for serine phosphorylation in insulin/angiotensin II crosstalk.
Folli F et al.
The Journal of Clinical Investigation, 100, 2158-2158 (1997)
Quantification of the Antioxidant Activity in Salt-Stressed Tissues.
Maksimovic JJD and Zivanovic BD
Plant Salt Tolerance: Methods and Protocols, 237-237 (2012)
Andreas U Müller et al.
Nature communications, 10(1), 4653-4653 (2019-10-13)
In mycobacteria, transcriptional activator PafBC is responsible for upregulating the majority of genes induced by DNA damage. Understanding the mechanism of PafBC activation is impeded by a lack of structural information on this transcription factor that contains a widespread, but
Structural analysis of N- and O-glycans released from glycoproteins.
Jensen PH et al.
Nature Protocols, 7, 1299-1299 (2012)

Protocolos

An introduction to both Northern and Southern blotting, popular methods for the transfer of macromolecules to membranous support. This article also offers a Southern blot protocol and a northern blot protocol.

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