PHR1013

Salicylic acid

Pharmaceutical Secondary Standard; Certified Reference Material

• Sinónimos: 2-Hydroxybenzoic acid
• Fórmula lineal: 2^-(HO)C₆H₄CO₂H
• Número de CAS: 69-72-7
• Peso molecular: 138.12
• Beilstein/REAXYS Number: 774890
• EC Number: 200-712-3
• MDL number: MFCD00002439
• UNSPSC Code: 41116107
• PubChem Substance ID: 329823044
• NACRES: NA.24

Propiedades

• grade: certified reference material; pharmaceutical secondary standard
• Quality Level: 300
• agency: traceable to BP 775; traceable to Ph. Eur. S020000; traceable to USP 1609002
• vapor density: 4.8 (vs air)
• vapor pressure: 1 mmHg ( 114 °C)
• API family: salicylic acid
• CofA: current certificate can be downloaded
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• bp: 211 °C (lit.)
• mp: 158-161 °C (lit.)
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-30°C
• SMILES string: OC(=O)c1ccccc1O
• InChI: 1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)
• InChI key: YGSDEFSMJLZEOE-UHFFFAOYSA-N

Descripción

General description

Salicylic acid is an important material in pharmaceutical industry, obtained via the decomposition of acetylsalicylic acid. Salicylic acid is widely used in food industry for producing dyes and artificial scents. It also shows therapeutic potential in protecting the skin from sun damage and hence finds applications in cosmetics and medicine.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Salicylic acid may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using spectrofluorometric technique.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC3036 in the slot below. This is an example certificate only and may not be the lot that you receive.

Recommended products

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Información de seguridad

• pictograms: GHS08,GHS05,GHS07
• signalword: Danger
• hcodes: H302,H318,H361d
• pcodes: P202 - P264 - P280 - P301 + P312 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 2
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: 314.6 °F - closed cup
• flash_point_c: 157 °C - closed cup