90970

γ-Butirolactona

analytical standard

• Sinónimos: γLactona del ácido hidroxibutírico, GBL, Lactona del ácido 4-hidroxibutírico
• Fórmula empírica (notación de Hill): C₄H₆O₂
• Número de CAS: 96-48-0
• Peso molecular: 86.09
• Beilstein/REAXYS Number: 105248
• EC Number: 202-509-5
• MDL number: MFCD00005386
• UNSPSC Code: 85151701
• PubChem Substance ID: 329769980
• NACRES: NA.24

Propiedades

• grade: analytical standard
• Quality Level: 100
• vapor density: 3 (vs air)
• vapor pressure: 1.5 mmHg ( 20 °C)
• assay: ≥99.0% (GC)
• autoignition temp.: 851 °F
• shelf life: limited shelf life, expiry date on the label
• expl. lim.: 16 %
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• impurities: ≤0.3% water
• refractive index: n20/D 1.436 (lit.)
• bp: 204-205 °C (lit.)
• mp: −45 °C (lit.)
• density: 1.12 g/mL at 25 °C (lit.)
• application(s): cleaning products; cosmetics; flavors and fragrances; food and beverages; personal care
• format: neat
• storage temp.: 2-8°C
• SMILES string: O=C1CCCO1
• InChI: 1S/C4H6O2/c5-4-2-1-3-6-4/h1-3H2
• InChI key: YEJRWHAVMIAJKC-UHFFFAOYSA-N

Descripción

General description

γ-Butyrolactone (GBL) is a related lactone analog of γ-hydroxybutyric acid (GHB), a widespread drug of abuse, identified as an endogenous constituent of the mammalian brain, in which it exhibits a strong central nervous system depressant effect. GBL is considered as a legal substitute of GHB, and commonly identified in beverages including coffee, apple cider vinegar, tea, carbonated drinks, etc.

Application

γ-Butyrolactone may be used as an analytical reference standard for the quantification of the analyte in roasted Italian chestnuts, wine samples, beverages using chromatography techniques.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Precursor del ácido γ-hidroxibutírico (GHB). Bloquea la liberación de dopamina al bloquear el flujo de impulsos en las neuronas dopaminérgicas. El pretratamiento con γ-butirolactona permite la detección de la liberación de dopamina inducida por autorreceptor.

Información de seguridad

• pictograms: GHS05,GHS07
• signalword: Danger
• hcodes: H302,H318,H336
• pcodes: P261 - P264 - P271 - P280 - P301 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - STOT SE 3
• target_organs: Central nervous system
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1
• flash_point_f: 208.4 °F - closed cup
• flash_point_c: 98 °C - closed cup