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50553

Sigma-Aldrich

α-Tri-Calcium phosphate

Reagent for transient & stable DNA transfections

Sinónimos:

α-TCP, α-Tricalcium phosphate

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About This Item

Fórmula lineal:
Ca3(PO4)2
Número de CAS:
7758-87-4
Peso molecular:
310.18
EC Number:
231-840-8
MDL number:
MFCD00015984
UNSPSC Code:
41106502
PubChem Substance ID:
329757609
NACRES:
NA.52

grade

for molecular biology

Quality Level

100

form

powder

technique(s)

transfection: suitable

application(s)

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care

storage temp.

room temp

SMILES string

[Ca++].[Ca++].[Ca++].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O

InChI

1S/3Ca.2H3O4P/c;;;2*1-5(2,3)4/h;;;2*(H3,1,2,3,4)/q3*+2;;/p-6

InChI key

QORWJWZARLRLPR-UHFFFAOYSA-H

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General description

α-tri-Calcium is a tasteless powder containing excess of calcium oxide. It is commonly used to introduce DNA and transfect eukaryotic cells for molecular biology experiments.
α-tri-Calcium phosphate (α-TCP) can be made by heating the low-temperature polymorph β-TCP. It can also be made by thermal crystallization of amorphous precursors with the appropriate composition above the transformation temperature. α-TCP is biocompatible as β-TCP. It is highly soluble and hydrolyses quickly to calcium-deficient hydroxyapatite. This makes α-TCP a beneficial constituent for formulating self-setting osteotransductive bone cements and biodegradable bioceramics and composites for bone repairing.

Application

For analysis of bone cement; as standard.
α-tri-Calcium phosphate has been used to transfect 293T and 231 cells with the PiggyBac LSS-mOrange- aspartate-glutamate-valine-aspartate (DEVD)-mKate2 transposon vector and in reporter verification studies.
Suitable for
  • transient and stable transfection of wide range of cell types
  • drug delivery systems

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
BCCG9468

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A Caspase-3 Reporter for Fluorescence Lifetime Imaging of Single-Cell Apoptosis
Buschhaus J, et al.
Cells, 7(6), 57-57 (2018)
alpha-Tricalcium phosphate: Synthesis, properties and biomedical applications
Carrodeguas R G and De A S
Acta Biomaterialia, 7(10), 3536-3546 (2011)
Timo Brandenburger et al.
Shock (Augusta, Ga.), 42(3), 234-238 (2014-07-01)
Remote ischemic preconditioning (RIPC) is an easily applicable method for protecting the heart against a subsequent ischemia and reperfusion (I/R) injury. However, the exact molecular mechanisms underlying RIPC are unknown. We examined the involvement of microRNAs (miRNAs) and in particular
Krzysztof W Luczynski et al.
Journal of biomedical materials research. Part A, 101(1), 138-144 (2012-07-25)
This paper is concerned with reliable and physically sound elasticity determination of rapid-prototyped tissue engineering scaffolds made of poly-L-lactide (PLLA), with and without small portions of tricalcium phosphate (TCP) inclusions. At the level of overall scaffolds, that is, that of
A H Choi et al.
Journal of dental research, 92(10), 853-859 (2013-07-17)
The purpose of coatings on implants is to achieve some or all of the improvements in biocompatibility, bioactivity, and increased protection from the release of harmful or unnecessary metal ions. During the last decade, there has been substantially increased interest
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