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50194

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Sulisobenzone

analytical standard

Sinónimos:

5-Benzoyl-4-hydroxy-2-methoxybenzenesulfonic acid, HMBS, Sulisobenzone

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About This Item

Fórmula empírica (notación de Hill):
C14H12O6S
Número de CAS:
4065-45-6
Peso molecular:
308.31
Beilstein/REAXYS Number:
2889165
EC Number:
223-772-2
MDL number:
MFCD00024962
UNSPSC Code:
41116107
PubChem Substance ID:
329757575
NACRES:
NA.24

grade

analytical standard

Quality Level

100

assay

≥97.5% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
environmental
food and beverages
personal care

format

neat

SMILES string

COc1cc(O)c(cc1S(O)(=O)=O)C(=O)c2ccccc2

InChI

1S/C14H12O6S/c1-20-12-8-11(15)10(7-13(12)21(17,18)19)14(16)9-5-3-2-4-6-9/h2-8,15H,1H3,(H,17,18,19)

InChI key

CXVGEDCSTKKODG-UHFFFAOYSA-N

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General description

Sulisobenzone is a broad spectrum organic UV filter in sunscreen formulations, known to absorb deleterious UV light.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Sulisobenzone may be used as an analytical reagent for the determination of the analyte in sunscreen formulations by high-performance liquid chromatography with UV spectrophotometric detection.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Aquatic Chronic 3 - Eye Irrit. 2 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

No data available

flash_point_c

No data available

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Certificados de análisis (COA)

Lot/Batch Number
BGBC3807V
BGBC3806V
BGBC3805V
BGBC3804V
BCBH0992V

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Sigma-Aldrich

Q1125

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2-Hydroxy-4-methoxybenzophenone 98%

Sigma-Aldrich

H36206

2-Hydroxy-4-methoxybenzophenone

Determination of UV-filters in sunscreens by HPLC.
Chisvert A, et al.
Fresenius Journal of Analytical Chemistry, 369(7-8), 638-641 (2001)
S M Edwards et al.
Photodermatology, photoimmunology & photomedicine, 10(3), 111-117 (1994-06-01)
The ability to accurately predict the phototoxic potential of personal and skin care products remains a key element in assessing the safety of premarketed products. To find a reliable in vitro alternative test for photoirritancy, the European Commission and the
M Jarratt et al.
Journal of the American Academy of Dermatology, 9(3), 354-360 (1983-09-01)
A PABA ester-oxybenzone preparation is superior to PABA or sulisobenzone alone in protecting the skin from methoxsalen-induced ultraviolet A (UVA) phototoxicity after water substantivity challenge. Such a mixture would be useful as a UVA screen for uninvolved or actinically damaged
C Augustin et al.
Photodermatology, photoimmunology & photomedicine, 13(1-2), 27-36 (1997-02-01)
Phototoxicity inducing in vivo photoirritation, a reversible inflammatory reaction of the skin after chemical contact and UVA radiation exposure, is increasingly observed as a side effect associated with the use of both cosmetics and systemic drugs. In order to systematically
Zacarías León et al.
Analytica chimica acta, 664(2), 178-184 (2010-04-07)
2-Hydroxy-4-methoxybenzophenone and 2-hydroxy-4-methoxybenzophenone-5-sulphonic acid, commonly known as benzophenone-3 (BZ3) and benzophenone-4 (BZ4), respectively, are substances widely used as UV filters in cosmetic products in order to absorb UV radiation and protect human skin from direct exposure to the deleterious wavelengths
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