27227-M

Acetato de etilo

puriss., meets analytical specification of Ph. Eur., BP, NF, ≥99.5% (GC)

• Sinónimos: EtOAc
• Fórmula lineal: CH₃COOC₂H₅
• Número de CAS: 141-78-6
• Peso molecular: 88.11
• Beilstein/REAXYS Number: 506104
• EC Number: 205-500-4
• MDL number: MFCD00009171
• UNSPSC Code: 12352108
• PubChem Substance ID: 329752987
• NACRES: NA.21

Propiedades

• vapor density: 3 (20 °C, vs air)
• Quality Level: 100
• vapor pressure: 73 mmHg ( 20 °C)
• grade: puriss.
• assay: ≥99.5% (GC)
• form: liquid
• autoignition temp.: 801 °F
• quality: meets analytical specification of Ph. Eur., BP, NF
• expl. lim.: 2.2-11.5 %, 38 °F
• impurities: residual solvents, complies; ≤0.005% free acid (as CH₃COOH); ≤0.01% methyl. comp.(as acetic acid methylester); ≤0.1% ethanol (GC); ≤0.10% water (Karl Fischer); ≤0.2% related subst. (GC)
• evapn. residue: ≤0.003%
• refractive index: n20/D 1.371-1.373; n20/D 1.3720 (lit.)
• bp: 76.5-77.5 °C (lit.)
• mp: −84 °C (lit.)
• density: 0.898-0.902 g/mL at 20 °C; 0.894-0.898 g/mL at 25 °C; 0.902 g/mL at 25 °C (lit.)
• suitability: complies for appearance of solution; complies for reaction against H₂SO₄; corresponds for chromatography; passes test for identity (IR)
• format: neat
• SMILES string: CCOC(C)=O
• InChI: 1S/C4H8O2/c1-3-6-4(2)5/h3H2,1-2H3
• InChI key: XEKOWRVHYACXOJ-UHFFFAOYSA-N

Descripción

General description

Ethyl acetate, a carboxylate ester, is a bio-friendly organic solvent with a wide range of industrial applications such as specialized or sensitive chemical synthesis & catalysis; reaction monitoring, metal-sensitive reactions, and highly sensitive purifications.

Application

• [Determination of 12 prohibited veterinary drug residues in pig urine by ultra high performance liquid chromatography-tandem mass spectrometry]: Ethyl acetate is utilized for sample preparation in this advanced method to detect drug residues in animal samples, emphasizing its role in veterinary pharmaceutical compliance (Wan et al., 2024).


• Therapeutic effect of Ginkgetin on smoke-induced airway inflammation by down-regulating the c/EBPβ signaling pathway and CCL2 expression: This study explores the anti-inflammatory properties of Ginkgetin, where ethyl acetate is used in the extraction process, highlighting its utility in biomedical research (Tao et al., 2024).


• Effect of methanol extract of Plectranthus esculentus N.E.Br tuber and its fractions on indices of benign prostatic hyperplasia in Wistar rats: Ethyl acetate is employed in the extraction of bioactive compounds for pharmacological studies, showing its critical role in therapeutic applications (Kanu et al., 2024).


• Phytochemical evaluation of Ziziphus mucronata and Xysmalobium undulutum towards the discovery and development of anti-malarial drugs: Demonstrates the use of ethyl acetate in phytochemical screenings, contributing to the development of new anti-malarial medications (Buthelezi et al., 2024).


• The First Records of the In Silico Antiviral and Antibacterial Actions of Molecules Detected in Extracts of Algerian Fir (Abies numidica De Lannoy) Using LC-MS/MS Analysis: This research utilizes ethyl acetate for extracting compounds from plants for antiviral and antibacterial testing, underscoring its importance in the study of natural products (Benouchenne et al., 2024).

Información de seguridad

• pictograms: GHS02,GHS07
• signalword: Danger
• hcodes: H225,H319,H336
• pcodes: P210 - P233 - P240 - P241 - P242 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
• target_organs: Central nervous system
• supp_hazards: EUH066
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 1
• flash_point_f: 26.6 °F - closed cup
• flash_point_c: -3.00 °C - closed cup