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MilliporeSigma

15209

Supelco

N,O-bis(trimetilsilil)trifluoroacetamida con trimetilclorosilano

for GC derivatization, LiChropur, contains 10% TMCS, 98% (excluding TMCS)

Sinónimos:

BSTFA + TMCS

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About This Item

Fórmula lineal:
CF3C[=NSi(CH3)3]OSi(CH3)3
Número de CAS:
Peso molecular:
257.40
Beilstein/REAXYS Number:
2050024
MDL number:
UNSPSC Code:
41116105
PubChem Substance ID:
NACRES:
NA.22

grade

for GC derivatization

Quality Level

assay

≥97.5% (excluding TMCS, GC)
98% (excluding TMCS)

form

liquid

quality

LiChropur

reaction suitability

reagent type: derivatization reagent
reaction type: Silylations

technique(s)

gas chromatography (GC): suitable

impurities

9.0-11.0% TMCS

refractive index

n20/D 1.384 (lit.)

bp

45-50 °C/14 mmHg (lit.)

density

0.97 g/mL (lit.)

SMILES string

C[Si](C)(C)O\C(=N\[Si](C)(C)C)C(F)(F)F

InChI

1S/C8H18F3NOSi2/c1-14(2,3)12-7(8(9,10)11)13-15(4,5)6/h1-6H3/b12-7+

InChI key

XCOBLONWWXQEBS-KPKJPENVSA-N

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General description

N,O-Bis(trimethylsilyl)trifluoroacetamide with trimethylchlorosilane has found application to be used in gas chromatography (GC) and mass-spectrometry (MS). It can also be used in HPLC- electrochemical detection assay of 8-oxo-deoxyguanosine and?8-oxo-guanine.

Application


  • Determination of Δ(9)-tetrahydrocannabinol, 11-nor-carboxy-Δ(9)-tetrahydrocannabinol and cannabidiol in human plasma and urine after a commercial cannabidiol oil product intake.: This study uses N,O-Bis(trimethylsilyl)trifluoroacetamide with trimethylchlorosilane for derivatization to enhance the sensitivity and accuracy of cannabinoid detection in biological samples. This method is vital for forensic toxicology and clinical research, providing reliable data for cannabinoid analysis (Papoutsis et al., 2024).

  • The impact of lipid degradation on fingerprint quality on fired firearm cartridges.: This research employs N,O-Bis(trimethylsilyl)trifluoroacetamide with trimethylchlorosilane to study lipid degradation and its effect on fingerprint quality on firearm cartridges. The findings are crucial for forensic science, particularly in improving methods for preserving and analyzing fingerprint evidence (Goulart et al., 2023).

  • Contaminants of emerging concern: Silylation procedures, evaluation of the stability of silyl derivatives and associated measurement uncertainty.: This paper evaluates the use of N,O-Bis(trimethylsilyl)trifluoroacetamide with trimethylchlorosilane in silylation procedures for environmental analysis. The study assesses the stability and measurement uncertainty of silyl derivatives, which is crucial for accurate monitoring of environmental contaminants (Ljoncheva et al., 2023).

  • Screening of Organic Acidurias by Gas Chromatography-Mass Spectrometry (GC-MS).: This research utilizes N,O-Bis(trimethylsilyl)trifluoroacetamide with trimethylchlorosilane in the derivatization process for screening organic acidurias. This method is significant for clinical diagnostics, providing a reliable approach for detecting metabolic disorders (Scott et al., 2022).

  • A sensitive, robust method for determining natural and synthetic hormones in surface and wastewaters by continuous solid-phase extraction-gas chromatography-mass spectrometry.: The study presents a method using N,O-Bis(trimethylsilyl)trifluoroacetamide with trimethylchlorosilane for the detection of hormones in environmental samples. This robust method is essential for monitoring water quality and detecting endocrine-disrupting compounds (Chafi and Ballesteros, 2022).


Other Notes

No se ha establecido de manera inequívoca la posición de los grupos sililo. Se le ha denominado N,N y N,O.

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Related product

Referencia del producto
Descripción
Precios

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1A

Storage Class

3 - Flammable liquids

wgk_germany

WGK 3

flash_point_f

15.8 °F - closed cup

flash_point_c

-9 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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