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MilliporeSigma

05164

Supelco

(Aminomethyl)phosphonic acid

PESTANAL®, analytical standard

Sinónimos:

AMPA

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About This Item

Fórmula lineal:
NH2CH2P(O)(OH)2
Número de CAS:
Peso molecular:
111.04
Beilstein/REAXYS Number:
1701219
MDL number:
UNSPSC Code:
77101502
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

PESTANAL®

assay

≥98.0% (TLC)

shelf life

limited shelf life, expiry date on the label

impurities

≤3.0% water (calc. from elemental analysis)

application(s)

agriculture
environmental

format

neat

SMILES string

NCP(O)(O)=O

InChI

1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5)

InChI key

MGRVRXRGTBOSHW-UHFFFAOYSA-N

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Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Seonil Kim et al.
Proceedings of the National Academy of Sciences of the United States of America, 112(10), 3122-3127 (2015-02-26)
Gene knockout (KO) does not always result in phenotypic changes, possibly due to mechanisms of functional compensation. We have studied mice lacking cGMP-dependent kinase II (cGKII), which phosphorylates GluA1, a subunit of AMPA receptors (AMPARs), and promotes hippocampal long-term potentiation
Mary L Huff et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 40(4), 861-873 (2014-09-27)
Recent findings suggest that the mesolimbic dopamine neurons, known to promote cocaine-seeking behavior, are strongly inhibited by a newly characterized region of the midbrain known as the rostromedial tegmental nucleus (RMTg). The RMTg appears to be involved in generating reward-prediction
Philip Jean-Richard Dit Bressel et al.
PloS one, 9(11), e111699-e111699 (2014-11-05)
The lateral habenula (LHb) is a small epithalamic structure that projects via the fasciculus retroflexus to the midbrain. The LHb is known to modulate midbrain dopamine (DA) neurons, including inhibition of ventral tegmental area (VTA) neurons via glutamatergic excitation of
W Zhou et al.
European psychiatry : the journal of the Association of European Psychiatrists, 29(7), 419-423 (2013-12-11)
Ketamine exerts fast acting, robust, and lasting antidepressant effects in a sub-anesthetic dose, however, the underlying mechanisms are still not fully elucidated. Recent studies have suggested that ketamine's antidepressant effects are probably attributed to the activation of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)
Einar Ö Einarsson et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 40(2), 480-487 (2014-08-06)
After acquisition, hippocampus-dependent memories undergo a systems consolidation process, during which they become independent of the hippocampus and dependent on the anterior cingulate cortex (ACC) for memory expression. However, consolidated remote memories can become transiently hippocampus-dependent again following memory reactivation.

Artículos

Glyphosate and related compounds are measured in oatmeal and infant cereal using ion-exchange polymer-based particles for HPLC and SPE. Low level detection was obtained.

A simplified LC-MS/MS method to determine glyphosate and related compounds using a Supel™ Carbon LC U/HPLC column for stability under higher pH conditions and sufficient retention for the polar analytes in the presence of methanol as an extraction solvent.

Protocolos

EPA Method 547 outlines the analysis of glyphosate in drinking water by direct aqueous injection HPLC, post column derivatization, and fluorescence detection

LC/MS Analysis of Glyphosate and Metabolites on apHera™ NH2, 2 mm I.D. Column

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