CBL1512F

Anti-Integrin αM [CD11b] Antibody, clone OX-42, FITC conjugated

clone OX-42, Chemicon^®, from mouse

• Sinónimos: CD11b
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propiedades

• biological source: mouse
• Quality Level: 100
• conjugate: FITC conjugate
• antibody product type: primary antibodies
• clone: OX-42, monoclonal
• species reactivity: rat
• manufacturer/tradename: Chemicon^®
• technique(s): flow cytometry: suitable; immunohistochemistry: suitable
• isotype: IgG2a
• NCBI accession no.: NM_000632.3
• UniProt accession no.: P11215
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: rat ... Itgam(25021)

Descripción

Specificity

This antibody recognizes most macrophages (including resident peritoneal and activated macrophages), kupffer cells, but only about 35% of alveolar macrophages. The antibody also labels dendritic cells extensively, granulocytes and cells with the morphology of microglia in brain. The antibody precipitates three polypeptides of 150, 103 and 95 KDa. The antibody inhibits complement mediated rosettes and is probably the rat equivalent of the human receptor for IC3b called CR3.
FUSION PARTNER: NSO myeloma cell line.

Application

Flow cytometry

Immunohistochemical studies of rat fresh frozen tissue sections following either periodate-lysine-paraformaldehyde (PLP) fixation, or acetone. Works on very lightly PFA fixed, frozen tissues. (perfusion only 4% PFA 10-15′ no post-fix).

Optimal working dilutions must be determined by the end user.

This Anti-Integrin αM CD11b Antibody, clone OX-42, FITC conjugated is validated for use in FC, IH for the detection of Integrin αM [CD11b].

Linkage

Replaces: MAB1404F

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable