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AB9209

Sigma-Aldrich

Anti-Metabotropic Glutamate Receptor 2 Antibody

Chemicon®, from rabbit

Sinónimos:

mGluR2

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

immunocytochemistry: suitable
immunohistochemistry: suitable (paraffin)
western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... GRM2(2912)

Specificity

Recognizes Metabotropic Glutamate Receptor 2 [mGluR2].

Immunogen

Synthetic peptide from the N-terminal extracellular domain of human Metabotropic Glutamate Receptor 2. The immunogen has 100% conservation with rat.

Application

Anti-Metabotropic Glutamate Receptor 2 Antibody detects level of Metabotropic Glutamate Receptor 2 & has been published & validated for use in IC, IH(P) & WB.
Research Category
Neuroscience
Research Sub Category
Neurotransmitters & Receptors
Western blot

Immunohistochemistry on formalin fixed paraffin embedded tissue sections.

Immunocytochemistry on acetone fixed cells.

Optimal working dilutions must be determined by the end user.

Physical form

Affinity purified immunoglobulin. Liquid in PBS, pH 7.7 with 0.01% sodium azide.

Storage and Stability

Maintain at -70°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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B Á Nic Dhonnchadha et al.
Behavioural brain research, 234(1), 100-106 (2012-06-23)
Extinguishing abnormally strengthened learned responses to cues associated with drugs of abuse remains a key tactic for alleviating addiction. To assist in developing pharmacotherapies to augment exposure therapy for relapse prevention, investigation into neurobiological underpinnings of drug-cue extinction learning is
Won-Mee Park et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 31(16), 5909-5920 (2011-04-22)
Coupling of neurons by electrical synapses (gap junctions) transiently increases in the mammalian CNS during development. We report here that the developmental increase in neuronal gap junction coupling and expression of connexin 36 (Cx36; neuronal gap junction protein) are regulated
Yongfu Wang et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 32(2), 713-725 (2012-01-13)
In the mammalian CNS, excessive release of glutamate and overactivation of glutamate receptors are responsible for the secondary (delayed) neuronal death following neuronal injury, including ischemia, traumatic brain injury (TBI), and epilepsy. The coupling of neurons by gap junctions (electrical
Haopeng Zhang et al.
Hippocampus, 25(11), 1299-1313 (2015-03-06)
Whereas the ionotropic glutamate receptors are the major mediator in glutamatergic transmission, the metabotropic glutamate receptors (mGluRs) usually play a modulatory role. Whereas the entorhinal cortex (EC) is an essential structure involved in the generation and propagation of epilepsy, the

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