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AB1559

Sigma-Aldrich

Anti-Adenosine A2a Receptor Antibody

serum, Chemicon®

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

pig, bovine, rat, human, canine

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
western blot: suitable

suitability

not suitable for immunohistochemistry

NCBI accession no.

NM_000675.4

UniProt accession no.

P29274

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... ADORA2A(135)

Immunogen

Synthetic 30 amino acid peptide corresponding to amino acids 383-412 of the canine adenosine A2a receptor near the C-terminal intracellular domain (30 amino acids) of the cloned canine A2a receptor. The A2a sequence selected in not present in A1, A2b and A3 receptors.

Application

This Anti-Adenosine A2a Receptor Antibody is validated for use in ELISA, WB for the detection of Adenosine A2a Receptor.
Western blot: 1:1,000-1:5,000 (Chemiluminescence technique), 40-100 μg membrane proteins/lane of striatal membranes. Higher concentrations of the antibody may be necessary if colorimetric detection or milk-based antibody diluent are used.

ELISA: 1:10,000-1:50,000 (50-100 ng A2aR peptide (Cat. Number AG285)/well)

Optimal working dilutions must be determined by end user.

Physical form

Rabbit antiserum. Liquid containing 0.1% sodium azide.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Astrocytic adenosine A2A receptors control the amyloid-? peptide-induced decrease of glutamate uptake.
Matos, Marco, et al.
Journal of Alzheimer'S Disease, 31, 555-567 (2012)
M E Olah et al.
Annual review of pharmacology and toxicology, 35, 581-606 (1995-01-01)
Adenosine receptors (ARs) are members of the G protein-coupled receptor family and mediate the multiple physiological effects of adenosine. Currently, four AR subtypes have been cloned: A1AR, A2aAR, A2bAR, and A3AR. All subtypes are distinctly distributed throughout the body and
Neurochemical and structural organization of the principal nucleus of the inferior olive in the human.
Joan S Baizer,Chet C Sherwood,Patrick R Hof,Sandra F Witelson,Fahad Sultan
Anatomical Record (Hoboken, N.J. : 2007) (2007)
Rod Phosphodiesterase-6 ( PDE6) Catalytic Subunits Restore Cone Function in a Mouse Model Lacking Cone PDE6 Catalytic sty
Kolandaivelu S, Chang B, Ramamurthy V
The Journal of Biological Chemistry null
Differential expression of adenosine receptors in human neutrophils: up-regulation by specific Th1 cytokines and lipopolysaccharide.
Fortin, A; Harbour, D; Fernandes, M; Borgeat, P; Bourgoin, S
Journal of Leukocyte Biology null
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