6.18300

Acetonitrilo

for chromatography (gradient grade 2.5)

• Sinónimos: ACN, Cianometano, Cianuro de metilo, Nitrilo de etilo
• Fórmula lineal: CH₃CN
• Número de CAS: 75-05-8
• Peso molecular: 41.05
• Beilstein/REAXYS Number: 741857
• MDL number: MFCD00001878
• UNSPSC Code: 12191502

Propiedades

• grade: for chromatography (gradient grade 2.5)
• Quality Level: 100
• vapor density: 1.41 (vs air)
• vapor pressure: 72.8 mmHg ( 20 °C)
• assay: ≥99.9% (GC)
• form: liquid
• autoignition temp.: 973 °F
• expl. lim.: 16 %
• technique(s): HPLC: suitable
• refractive index: n20/D 1.344 (lit.)
• bp: 81-82 °C (lit.)
• mp: −45 °C (lit.)
• solubility: water: soluble (1,000 g/l at 25 °C (77 °F))
• density: 0.786 g/mL at 25 °C (lit.)
• application(s): general analytical
• SMILES string: CC#N
• InChI: 1S/C2H3N/c1-2-3/h1H3
• InChI key: WEVYAHXRMPXWCK-UHFFFAOYSA-N

Descripción

General description

Acetonitrile is commonly used as a key component in the mobile phase for gradient elution chromatography. It is used in various chromatographic techniques, such as high-performance liquid chromatography (HPLC) and liquid chromatography-mass spectrometry (LC-MS).

Application

Acetonitrile can be used as a mobile phase:

• Buffer in the liquid chromatographic method for determination of polyamines, amino acids, metanephrines, and catecholamine compounds in human body fluids.
• Component to facilitate the fast gradient elution separations of polar neutral active pharmaceutical ingredients (APIs).

Información de seguridad

• pictograms: GHS02,GHS07
• signalword: Danger
• hcodes: H225,H302 + H312 + H332,H319
• pcodes: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 2
• flash_point_f: 35.6 °F - closed cup
• flash_point_c: 2.0 °C - closed cup