5.04913

Aniracetam

• Sinónimos: Aniracetam, 1-(4-methoxybenzoyl)pyrrolidin-2-one, Draganon, Sarpul, Ampamet, Memodrin, Referan, Memodrin, Referan, 1-(4-methoxybenzoyl)pyrrolidin-2-one, Draganon, Sarpul, Ampamet
• Fórmula empírica (notación de Hill): C₁₂H₁₃NO₃
• Número de CAS: 72432-10-1
• Peso molecular: 219.24
• MDL number: MFCD00153767
• UNSPSC Code: 12352200

Propiedades

• assay: ≥99% (HPLC)
• Quality Level: 100
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; protect from light
• color: white
• solubility: DMSO: 100 mM
• storage temp.: 2-8°C
• InChI: 1S/C12H13NO3/c1-16-10-6-4-9(5-7-10)12(15)13-8-2-3-11(13)14/h4-7H,2-3,8H2,1H3
• InChI key: ZXNRTKGTQJPIJK-UHFFFAOYSA-N

Descripción

General description

A positive allosteric modulator selective for AMPA receptors. Slows down AMPA receptor deactivation rate without altering the agonist potency. A leading candidate of ampakine nootropic for cognitive enhancement. Widely used in studies in a variety of brain functions (i.e. learn and memory, cognition) and disorders (depression, anxiety disorder, Alzheimer′s disease, and aging).

A positive allosteric modulator selective for AMPA receptors. Slows down AMPA receptor deactivation rate without altering the agonist potency. A leading candidate of ampakine nootropic for cognitive enhancement. Widely used in studies in a variety of brain functions (i.e. learn and memory, cognition) and disorders (depression, anxiety disorder, Alzheimer′s disease, and aging).

Please note that the molecular weight for this compound is batch-specific due to variable water content.

Biochem/physiol Actions

Primary Target
AMPA receptors

Warning

Toxicity: Standard Handling (A)

Other Notes

Koliaki, C., et al. 2012. CNS Neuroscience & Therapeutics.18, 302.
Lynch, G., et al. 2011. Pharmacol. Biochem. Behav.99, 116.
Nakamura, K., et al. 2001. Eur. J. Pharmacol.420, 33.
Ito, I. et al., 1990. J. Physiol.424, 553.
Isaacson et al., 1991. PNAS.88, 1093.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable