218744

Caspase-2 Inhibitor I

The Caspase-2 Inhibitor I controls the biological activity of Caspase-2. This small molecule/inhibitor is primarily used for Cancer applications.

• Sinónimos: Caspase-2 Inhibitor I, Z-VD(OMe)VAD(OMe)-FMK
• Fórmula empírica (notación de Hill): C₃₂H₄₆FN₅O₁₁
• Peso molecular: 695.73
• UNSPSC Code: 12352200
• NACRES: NA.54

Propiedades

• Quality Level: 100
• assay: ≥95% (HPLC); ≥95% (TLC)
• form: lyophilized
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; desiccated
• solubility: DMSO: 5 mg/mL
• shipped in: ambient
• storage temp.: −20°C

Descripción

General description

A cell-permeable and irreversible inhibitor of caspase-2 (ICH-1)

An irreversible inhibitor of caspase-2 (ICH-1).

Biochem/physiol Actions

Cell permeable: yes

Primary Target
caspase-2

Product does not compete with ATP.

Reversible: no

Warning

Toxicity: Standard Handling (A)

Sequence

Z-Val-Asp(OMe)-Val-Ala-Asp(OMe)-CH₂F*

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Gregoli, P.A., and Bondurant, M.C. 1999. J. Cell Physiol. 178, 133.
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable