218739

Caspase-1 Substrate X, Fluorogenic

A fluorogenic substrate for detecting caspase-1 (ICE), caspase-4, and caspase-5 activity.

• Sinónimos: Caspase-1 Substrate X, Fluorogenic, Caspase-5 Substrate III, Fluorogenic, Ac-WEHD-AMC
• Fórmula empírica (notación de Hill): C₃₈H₄₀N₈O₁₁
• Número de CAS: 189275-74-9
• Peso molecular: 784.77
• UNSPSC Code: 12352200
• NACRES: NA.54

Propiedades

• Quality Level: 100
• assay: ≥95% (HPLC)
• form: lyophilized
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; desiccated; protect from light
• solubility: DMSO: 5 mg/mL
• fluorescence: λ_ex 365–380 nm; λ_em 430–460 nm
• shipped in: ambient
• storage temp.: −20°C

Descripción

General description

A fluorogenic substrate for detecting caspase-1 (ICE) (excitation maximum: ~365-380 nm; emission maximum: ~430-460 nm).

A fluorogenic substrate for detecting caspase-1 (ICE), caspase-4, and caspase-5 activity.

Biochem/physiol Actions

Cell permeable: no

Product does not compete with ATP.

Reversible: no

Warning

Toxicity: Standard Handling (A)

Sequence

Ac-Trp-Glu-His-Asp-AMC

Other Notes

Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Thornberry, N.A., et al. 1997. J. Biol. Chem. 272, 17907.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable