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Documentos clave

14-343

Sigma-Aldrich

FKHR Protein, 100 µg

N-terminal, Glutathione-Stransferase (GST) tagged, full-length fusion protein corresponding to human FKHR.

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About This Item

UNSPSC Code:
12352200
eCl@ss:
32160405
NACRES:
NA.32

biological source

human

mol wt

Mw 105 kDa

manufacturer/tradename

Upstate®

technique(s)

activity assay: suitable (kinase)
western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

dry ice

Gene Information

human ... FOXO1(2308)

General description

Product Source: Recombinant human expressed in E. coli

Application

N-terminal, Glutathione-Stransferase (GST) tagged, full-length fusion protein corresponding to human FKHR.

Quality

routinely evaluated by phosphorylation by Akt1

Physical form

Glutathione-agarose

Storage and Stability

1 year at -70°C

Other Notes

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Skin Sens. 1

Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Arthur Bikbaev et al.
Scientific reports, 5, 14527-14527 (2015-09-30)
The formation and maintenance of connectivity are critically important for the processing and storage of information in neuronal networks. The brain extracellular matrix (ECM) appears during postnatal development and surrounds most neurons in the adult mammalian brain. Importantly, the removal
Young J Kim et al.
Neuron, 100(5), 1180-1193 (2018-10-23)
Considerable evidence suggests loss-of-function mutations in the chromatin remodeler CHD2 contribute to a broad spectrum of human neurodevelopmental disorders. However, it is unknown how CHD2 mutations lead to impaired brain function. Here we report mice with heterozygous mutations in Chd2
Stephen K Grady et al.
PloS one, 8(9), e73357-e73357 (2013-09-12)
The neural mechanisms of somatosensory information processing in the rodent vibrissae system are a topic of intense debate and research. Certain hypotheses emphasize the importance of stick-slip whisker motion, high-frequency resonant vibrations, and/or the ability to decode complex textures. Other
Stefan Weigel et al.
Journal of neurophysiology, 107(2), 640-648 (2011-10-28)
The midbrain is an important processing area for sensory information in vertebrates. The optic tectum and its mammalian counterpart, the superior colliculus, receive multimodal, topographic information and contain a sensory map that plays a role in spatial attention and orientation
Andrew J Weitz et al.
Neuron, 104(6), 1153-1167 (2019-11-02)
Anatomical and behavioral data suggest that the ventrolateral orbitofrontal cortex (VLO), which exhibits extensive connectivity and supports diverse sensory and cognitive processes, may exert global influence over brain activity. However, this hypothesis has never been tested directly. We applied optogenetic

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