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Key Documents

12-355

Sigma-Aldrich

SAMS Peptide

liquid, for Kinase Assays

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About This Item

UNSPSC Code:
12352202
eCl@ss:
32160405
NACRES:
NA.41

product name

SAMS Peptide, SAMS Peptide primarily used in Kinase Assays.

biological source

synthetic

Quality Level

form

liquid

manufacturer/tradename

Upstate®

technique(s)

activity assay: suitable (kinase)

NCBI accession no.

UniProt accession no.

shipped in

dry ice

Biochem/physiol Actions

Protein Target: AMPK (α1, β1, γ1)
Target Sub-Family: CAMK

Quality

Routinely evaluated by Peptide Phosphorylation Assay. SAMS Peptide was phosphorylated by AMP activated enzyme in the presence and absence of AMP.

Physical form

sterile distilled water

Storage and Stability

2 years at -20°C

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class

12 - Non Combustible Liquids

wgk_germany

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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S P Davies et al.
European journal of biochemistry, 186(1-2), 123-128 (1989-12-08)
1. We have synthesized two peptides, one based on the exact sequence around the unique site (Ser79) for the AMP-activated protein kinase on rat acetyl-CoA carboxylase (SSMS peptide) and another in which the serine residue corresponding to the site for
D G Hardie et al.
Annual review of biochemistry, 67, 821-855 (1998-10-06)
Mammalian AMP-activated protein kinase and yeast SNF1 protein kinase are the central components of kinase cascades that are highly conserved between animals, fungi, and plants. The AMP-activated protein kinase cascade acts as a metabolic sensor or "fuel gauge" that monitors
Purification and characterization of the AMP-activated protein kinase. Copurification of acetyl-CoA carboxylase kinase and 3-hydroxy-3-methylglutaryl-CoA reductase kinase activities.
Carling, D, et al.
European Journal of Biochemistry, 186, 129-136 (1989)
Ming-Hui Zou et al.
The Journal of biological chemistry, 278(36), 34003-34010 (2003-06-26)
AMP-activated kinase (AMPK) is a fuel-sensing enzyme present in most mammalian tissue. In response to a decrease in the energy state of a cell AMPK is phosphorylated and activated by still poorly characterized upstream events. Exposure of bovine aortic endothelial

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