104662
Cellvento® ModiFeed Sial+ COMP
Chemically defined cell culture feed - EMPROVE® CCM
Fabricación farmacéutica
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About This Item
UNSPSC Code:
41106213
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Quality Level
description
shipped with cooling packs
product line
Cellvento®
form
dry powder
greener alternative product characteristics
Design for Energy Efficiency
Learn more about the Principles of Green Chemistry.
sustainability
Greener Alternative Product
technique(s)
cell culture | mammalian: suitable
greener alternative category
storage temp.
2-8°C
General description
Cellvento® ModiFeed Sial+ COMP is part of the ModiFeed platform. It is a highly concentrated, one-part, pH neutral feed added to replenish depleted nutrients required for cellular function and to extend the production phase in fed-batch mode, while simultanously maximizing sialylation on the protein of interest. It is recommended combination with the production media Cellvento® 4CHO and EX-CELL® Advanced CHO or other production media.
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Application
Control of protein glycosylation, such as sialylation, while maximizing productivity is key for successful therapeutic protein development and production. N-glycoslyations of IgG Fc, particularly sialylation, has been reported to exert significant anti-inflammatory effects. High sialylation levels can help to increase stability, safety, and efficacy of the protein of interest. Cellvento® ModiFeed Sial+ COMP was developed to increase sialylation while maintaining or improving titer in CHO fed-batch processes
Features and Benefits
- Reduced complexity in fed-batch process
- Complete feed maximizing galactosylation
- Highly concentrated to reduce required feed volume
- Compacted format for conventient handling
- Higher liquid feed stability at room temperature
Quantity
Formulated to contain 155.8 grams of powder per liter of feed.
Legal Information
CELLVENTO is a registered trademark of Merck KGaA, Darmstadt, Germany
EX-CELL is a registered trademark of Merck KGaA, Darmstadt, Germany
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
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Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
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