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MilliporeSigma

C-035

Supelco

(±)-Cotinine-d3 solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

Sinónimos:

(+/-)-Cotinine-d3 solution

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About This Item

Fórmula empírica (notación de Hill):
C10H9D3N2O
Número de CAS:
Peso molecular:
179.23
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

certified reference material

Quality Level

form

liquid

feature

SNAP-N-SPIKE®, SNAP-N-SHOOT®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

forensics and toxicology

format

single component solution

storage temp.

−20°C

InChI

1S/C10H12N2O/c1-12-9(4-5-10(12)13)8-3-2-6-11-7-8/h2-3,6-7,9H,4-5H2,1H3/i1D3

InChI key

UIKROCXWUNQSPJ-FIBGUPNXSA-N

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General description

Cotinine is an alkaloid found in tobacco as well as a major urinary metabolite of nicotine. This stable-labeled internal standard is suitable for quantitation of cotinine levels in urine, blood, and saliva for GC/MS or LC-MS/MS applications in nicotine testing or clinical and diagnostic testing of nicotine biomarkers.

Application


  • (±)-Cotinine-d₃ solution in nicotine metabolism research: This stable isotope-labeled compound is utilized in the HPLC-MS analysis of nicotine and cotinine across various biological matrices, highlighting its critical role in advancing our understanding of nicotine metabolism and exposure in biomedical studies (Jin et al., 2022).

  • Biomarker analysis in passive smoking: Cotinine-d₃ serves as an internal standard in the precise quantification of urinary cotinine, aiding in the assessment of second-hand smoke exposure, particularly in pediatric health studies (Wang et al., 2014).

  • Enhanced analytical techniques for smoking cessation: Employed in a sophisticated UPLC-MS/MS setup, cotinine-d₃ is crucial for quantifying smoking-related biomarkers in clinical trials aimed at evaluating smoking cessation interventions, ensuring accurate and sensitive biomarker tracking (Dobrinas et al., 2011).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Related product

Referencia del producto
Descripción
Precios

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes

Storage Class

3 - Flammable liquids

wgk_germany

WGK 2

flash_point_f

51.8 °F - closed cup

flash_point_c

11.0 °C - closed cup


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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