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LM1102

Avanti

17:0-20:4 PE

Avanti Research™ - A Croda Brand LM1102, methanol solution

Sinónimos:

1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine

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About This Item

Fórmula empírica (notación de Hill):
C42H76NO8P
Número de CAS:
253127-52-5
Peso molecular:
754.03
UNSPSC Code:
12352211
NACRES:
NA.25

form

methanol solution

packaging

pkg of 1 × 1 mL (LM1102-1EA)

manufacturer/tradename

Avanti Research™ - A Croda Brand LM1102

concentration

~10 μg/mL (Refer to C of A for lot specific concentration.)

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCCC)=O

InChI

1S/C42H76NO8P/c1-3-5-7-9-11-13-15-17-19-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43)38-48-41(44)34-32-30-28-26-24-22-18-16-14-12-10-8-6-4-2/h11,13,17,19,21,23,27,29,40H,3-10,12,14-16,18,20,22,24-26,28,30-39,43H2,1-2H3,(H,46,47)/b13-1

InChI key

PWFGSGJBCRORHV-DVHMRFIGSA-N

Application

17:0-20:4 PE or 1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine has been used as an internal standard:
  • for phospholipid extraction from mitochondria for quantitative mass spectrometry (MS) analysis
  • for lipid analysis of murine brain lipid extract using Fourier transform-ion cyclotron resonance-mass spectrometry (FT-ICR-MS)
  • for lipid quantification using liquid chromatography- mass spectrometry (LC-MS)
  • in the preparation of total lipid extracts by LC-MS
  • for ratiometric quantification of phosphoethanolamine (PE) using LC-MS

Biochem/physiol Actions

Phosphoethanolamine (PE) acts as a substrate for several phospholipids of the cell membrane. It is associated with the phospholipid turnover. PE is also found to prevent tumor progression.

Packaging

2 mL Amber Glass Sealed Ampule (LM1102-1EA)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

also commonly purchased with this product

Referencia del producto
Descripción
Precios

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes

Storage Class

3 - Flammable liquids

wgk_germany

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

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Certificados de análisis (COA)

Lot/Batch Number

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Di Ding et al.
Molecular neurobiology, 56(4), 2618-2639 (2018-07-28)
Neurons from the adult central nervous system (CNS) demonstrate limited mRNA transport and localized protein synthesis versus developing neurons, correlating with lower regenerative capacity. We found that deimination (posttranslational conversion of protein-bound arginine into citrulline) undergoes upregulation during early neuronal
Kallol Gupta et al.
Nature protocols, 13(5), 1106-1120 (2018-04-28)
With the recent success in determining membrane protein structures, further detailed understanding of the identity and function of the bound lipidome is essential. Using an approach that combines high-energy native mass spectrometry (HE-nMS) and solution-phase lipid profiling, this protocol can
Milena Vukotic et al.
Molecular cell, 67(3), 471-483 (2017-07-18)
Mutations in mitochondrial acylglycerol kinase (AGK) cause Sengers syndrome, which is characterized by cataracts, hypertrophic cardiomyopathy, and skeletal myopathy. AGK generates phosphatidic acid and lysophosphatidic acid, bioactive phospholipids involved in lipid signaling and the regulation of tumor progression. However, the

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