890820C

18:0 DAP

Avanti Research^™ - A Croda Brand 890820C

• Sinónimos: 1,2-distearoyl-3-dimethylammonium-propane
• Fórmula empírica (notación de Hill): C₄₁H₈₁NO₄
• Número de CAS: 121315-93-3
• Peso molecular: 652.09
• UNSPSC Code: 12352211
• NACRES: NA.25

Propiedades

• form: liquid
• packaging: pkg of 1 × 2.5 mL (890820C-25mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 890820C
• concentration: 10 mg/mL (890820C-25mg)
• lipid type: transfection; cationic lipids
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: [H]C(CN(C)C)(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O
• InChI: 1S/C41H81NO4/c1-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-40(43)45-38-39(37-42(3)4)46-41(44)36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-2/h39H,5-38H2,1-4H3
• InChI key: RVBUSVJSKGVQQS-UHFFFAOYSA-N

Descripción

Application

1,2-distearoyl-3-dimethylammonium-propane (18:0 DAP) might be used to formulate lipid nanoparticles (LNPs) and to test its efficiency of packaging mRNA into an LNP. It might also be used in the preparation of “bubble liposomes” (BLs).

Biochem/physiol Actions

1,2-distearoyl-3-dimethylammonium-propane (18:0 DAP) is a cationic lipid and serves as a pH-sensitive transfection reagent.

Packaging

5 mL Clear Glass Sealed Ampule (890820C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Información de seguridad

• pictograms: GHS06,GHS08
• signalword: Danger
• hcodes: H302,H315,H319,H331,H336,H351,H361d,H372
• pcodes: P201 - P260 - P264 - P280 - P304 + P340 + P311 - P403 + P233
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• target_organs: Central nervous system
• wgk_germany: WGK 3