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878112P

Avanti

C16-18:1 PC

Avanti Research™ - A Croda Brand 878112P, powder

Sinónimos:

1-O-hexadecyl-2-oleoyl-sn-glycero-3-phosphocholine

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About This Item

Fórmula empírica (notación de Hill):
C42H84NO7P
Número de CAS:
95403-34-2
Peso molecular:
746.09
MDL number:
MFCD11974148
UNSPSC Code:
12352211
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 5 mg (878112P-5mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 878112P

lipid type

bioactive lipids
phosphoglycerides

shipped in

dry ice

storage temp.

−20°C

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C\CCCCCCCC)=O)COCCCCCCCCCCCCCCCC)=O

InChI key

SIEDNCDNGMIKST-IYEJTHTFSA-N

Categorías relacionadas

General description

C16-18:1 PC, also called as 1-O-hexadecyl-2-oleoyl-sn-glycero-3-phosphocholine (HOPC), is a member of platelet-activating factor (PAF) family of glycerophospholipids. HOPC is a mono-ether PC containing ester-linked 18:1 chain (oleoyl) at the sn-2 position and an ether-linked 16:0 chain (hexadecyl) at the sn-1 position.

Application

C16-18:1 PC or 1-O-hexadecyl-2-oleoyl-sn-glycero-3-phosphocholine may be used in the liposome binding assay. It may also be used as a lipid standard for quantification of glycerophosphocholine by liquid chromatography–mass spectrometry (LC–MS).

Biochem/physiol Actions

Platelet-activating factor (PAF), a lipid mediator acts as a pro-inflammatory agent that exhibits variety of biological and pharmacological effects.

Packaging

5 mL Clear Glass Sealed Ampule (878112P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

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Certificados de análisis (COA)

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Saki Yamaura et al.
Clinica chimica acta; international journal of clinical chemistry, 481, 184-188 (2018-03-20)
Measurement of lipoprotein-associated phospholipase A2 (Lp-PLA2) can be used as an adjunct to traditional cardiovascular risk factors for identifying individuals at higher risk of cardiovascular events. This can be performed by quantification of the protein concentration using an ELISA platform
John J H Shin et al.
Developmental cell, 52(4), 461-476 (2020-01-14)
Phosphoinositides, diacylglycerolpyrophosphate, ceramide-1-phosphate, and phosphatidic acid belong to a unique class of membrane signaling lipids that contain phosphomonoesters in their headgroups having pKa values in the physiological range. The phosphomonoester headgroup of phosphatidic acid enables this lipid to act as

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