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MilliporeSigma

855810P

Avanti

26:0 Lyso PC

1-hexacosanoyl-2-hydroxy-sn-glycero-3-phosphocholine, powder

Sinónimos:

1-hexacosanoyl-sn-glycero-3-phosphocholine; PC(26:0/0:0)

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About This Item

Fórmula empírica (notación de Hill):
C34H70NO7P
Número de CAS:
Peso molecular:
635.90
UNSPSC Code:
51191904
NACRES:
NA.25

assay

>99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC)

form

powder

packaging

pkg of 1 × 10 mg (855810P-10mg)
pkg of 1 × 25 mg (855810P-25mg)
pkg of 1 × 5 mg (855810P-5mg)

manufacturer/tradename

Avanti Research - A Croda Brand 855810P

shipped in

dry ice

storage temp.

−20°C

General description

Lysophosphatidylcholine (LPC) is a bioactive proinflammatory lipid, which has a choline group at its polar head. It is produced by pathological response.

Application

26:0 Lyso PC has been used as an internal standard for C26:0-lysophosphatidylcholine (LPC) extraction.

Biochem/physiol Actions

Lysophosphatidylcholine (LPC) induces many second messengers including, protein kinase C, extracellular-signal-regulated kinases and protein tyrosine kinases. It alters various biological functions in different cell types, including endothelial cells, smooth muscle cells, monocytes, macrophages and T-cells. LPC is linked to atherosclerosis and inflammatory diseases.

Packaging

5 mL Amber Glass Screw Cap Vial (855810P-10mg)
5 mL Amber Glass Screw Cap Vial (855810P-25mg)
5 mL Amber Glass Screw Cap Vial (855810P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Visite la Librería de documentos

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Genetics in medicine : official journal of the American College of Medical Genetics (2020-04-21)
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Hartley MD, et al.
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Analysis of phospholipid species in rat peritoneal surface layer by liquid chromatography/electrospray ionization ion-trap mass spectrometry
Gao F, et al.
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1761(7), 667-676 (2006)
Kelsey B Law et al.
Autophagy, 13(5), 868-884 (2017-05-20)
Peroxisome biogenesis disorders (PBDs) are metabolic disorders caused by the loss of peroxisomes. The majority of PBDs result from mutation in one of 3 genes that encode for the peroxisomal AAA ATPase complex (AAA-complex) required for cycling PEX5 for peroxisomal
Role of lysophosphatidylcholine (LPC) in atherosclerosis
Matsumoto T, et al.
Current Medicinal Chemistry, 14(30), 3209-3220 (2007)

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