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MilliporeSigma

850374P

Avanti

18:1 (Δ6-Cis) PC

1,2-dipetroselenoyl-sn-glycero-3-phosphocholine, powder

Sinónimos:

1,2-dipetroselinoyl-sn-glycero-3-phosphocholine; PC(18:1(6Z)/18:1(6Z))

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About This Item

Fórmula empírica (notación de Hill):
C44H84NO8P
Número de CAS:
Peso molecular:
786.11
UNSPSC Code:
51191904
NACRES:
NA.25

assay

>99% (TLC)

form

powder

packaging

pkg of 2 × 100 mg (850374P-200mg)
pkg of 1 × 25 mg (850374P-25mg)

manufacturer/tradename

Avanti Research - A Croda Brand 850374P

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCC/C=C\CCCCCCCCCCC)=O)COC(CCCC/C=C\CCCCCCCCCCC)=O)=O

General description

18:1 (Δ6-Cis) PC (1,2-dipetroselenoyl-sn-glycero-3-phosphocholine), a lipid derivative is made up of a phosphocholine backbone. It has two18 carbon fatty acid chains, each having one cis double bond at the 6th carbon.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Application

18:1 (Δ6-Cis) PC (1,2-dipetroselenoyl-sn-glycero-3-phosphocholine) may be used:
  • to generate sn-1 C18:1(Δ6-cis)- lysophosphatidylcholine (LPC) and sn-1 C18:1(Δ9-cis)-LPC standards for structural characterization of lysophosphatidylcholine (LPC) species by tandem electrospray ionization-linear ion trap-mass spectrometry (ESI-LIT-MS)
  • to study the effect on α-secretase activity in SH-SY5Y membranes
  • in liposome to study the effect of its acyl chain length and bond saturation on pore formation

Biochem/physiol Actions

Phosphatidylcholines (PCs) help to reduce the level of blood lipid and cholesterol.

Packaging

5 mL Clear Glass Sealed Ampule (850374P-200mg)
5 mL Clear Glass Sealed Ampule (850374P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Marcus O W Grimm et al.
International journal of molecular sciences, 14(3), 5879-5898 (2013-03-15)
Alzheimer's disease (AD) is characterized by extracellular accumulation of amyloid-β peptide (Aβ), generated by proteolytic processing of the amyloid precursor protein (APP) by β- and γ-secretase. Aβ generation is inhibited when the initial ectodomain shedding is caused by α-secretase, cleaving

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