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840072P

Avanti

Soy Lyso PC

Avanti Research™ - A Croda Brand 840072P, powder

Sinónimos:

L-α-lysophosphatidylcholine (Soy)

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About This Item

Número de CAS:
97281-38-4
UNSPSC Code:
12352211
NACRES:
NA.25

assay

>99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC)

form

powder

packaging

pkg of 2 × 100 mg (840072P-200mg)
pkg of 1 × 25 mg (840072P-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 840072P

lipid type

phospholipids
phosphoglycerides

shipped in

dry ice

storage temp.

−20°C

SMILES string

O[C@](COP([O-])(OCC[N+](C)(C)C)=O)([H])COC(CCCCCCCCCCCCCCC)=O

InChI

1S/C24H50NO7P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-24(27)30-21-23(26)22-32-33(28,29)31-20-19-25(2,3)4/h23,26H,5-22H2,1-4H3/t23-/m1/s1

InChI key

ASWBNKHCZGQVJV-HSZRJFAPSA-N

Categorías relacionadas

General description

Lyso Phosphatidylcholine (LPC) or lysolecithin is a minor phospholipid in plasma (8-12%) and cellular membranes (<3%).

Application

Soy Lyso PC has been used in the synthesis of 15-methylhexadecanoic acid (15-MHDA) and glycerophospholipids.

Biochem/physiol Actions

Soy Lyso phosphocholine or phosphotidylcholine (PC) is among the other lipids present in soybean lecithin. Lysophosphatidylcholine (LPC) is a bioactive proinflammatory lipid. It is generated during pathological activities and is implicated in atherosclerosis and inflammatory diseases. LPC modifies the functions of numerous cell-types, including smooth muscle cells, endothelial cells, macrophages, monocytes, and T-cells. LPC activates several second messengers and is involved in signal transduction mechanisms.

Packaging

5 mL Clear Glass Sealed Ampule (840072P-200mg)
5 mL Clear Glass Sealed Ampule (840072P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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The use of natural and synthetic phospholipids as pharmaceutical excipients
van Hoogevest P and Wendel A
European Journal of Lipid Science and Technology, 116(9), 1088-1107 (2014)
Lysophosphatidylcholine (lysolecithin) and its synthetic analogues. Immunemodulating and other biologic effects
Munder, PG and Modolell, M and Andreesen, Reinhard and Weltzien, HU and Westphal, O
Seminars in Immunopathology, 2(2), 187-203 (1979)
Thomas Linemann et al.
Pharmaceutics, 5(2), 246-260 (2013-12-05)
The aim of the present study was to evaluate the transfection potential of chitosan-coated, green-fluorescent magnetic nanoparticles (MNPs) (chi-MNPs) after encapsulation inside polyethylglycol (PEG)ylated liposomes that produced lipid-encapsulated chitosan-coated MNPs (lip-MNPs), and also to evaluate how these particles would distribute
High-Throughput Plasma Lipidomics: Detailed Mapping of the Associations with Cardiometabolic Risk Factors
Huynh K, et al.
Cell Chemical Biology, 26(1), 71-84 (2019)
Role of lysophosphatidylcholine (LPC) in atherosclerosis
Matsumoto T, et al.
Current Medicinal Chemistry, 14(30), 3209-3220 (2007)

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