810262P
Avanti
C11 TopFluor™ Ceramide
N-[11-(dipyrrometheneboron difluoride)undecanoyl]-D-erythro-sphingosine, powder
Sinónimos:
N-[11-(TopFluor)undecanoyl]-D-erythro-sphingosine
Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
About This Item
Fórmula empírica (notación de Hill):
C42H70N3O3F2
Número de CAS:
Peso molecular:
703.02
UNSPSC Code:
12352211
NACRES:
NA.25
Productos recomendados
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 250 μg (810262P-250ug)
manufacturer/tradename
Avanti Research™ - A Croda Brand 810262P
shipped in
dry ice
storage temp.
−20°C
General description
Ceramide, a bioactive sphingolipid belongs to the sphingolipid family of cell lipids. This pore-forming member is insoluble in water. It is a hygroscopic and light sensitive lipid.
Application
C11 TopFluor™ Ceramide may be used:
- in the ceramide and B-cell lymphoma-extra-large (Bcl-xL) binding studies to study the effect on ceramide channel formation
- as a tracer in confocal microscopy to treat T84 cells in order to study its localization in sphingomyelinase (SMase)-induced F-actin structures
- to study its effect on the migration of pancreatic cancer stem cells (PCSC) using confocal microscopy
Biochem/physiol Actions
Ceramide is known to participate in apoptosis, mediated by mitochondria. Ceramide channels plays a key role in the onset of apoptosis in vivo.
Packaging
5 mL Amber Glass Screw Cap Vial (810262P-250ug)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC
Storage Class
11 - Combustible Solids
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
¿Ya tiene este producto?
Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.
Microbial sphingomyelinase induces RhoA-mediated reorganization of the apical brush border membrane and is protective against invasion
Saslowsky DE, et al.
Molecular Biology of the Cell, 27(7), 1120-1130 (2016)
Ceramide Channels: Destabilization by Bcl-xL and Role in Apoptosis
Chang KT, et al.
Biochimica et Biophysica Acta, 1848(10 0 0), 2374-2374 (2015)
Pancreatic ductal adenocarcinoma cell secreted extracellular vesicles containing ceramide-1-phosphate promote pancreatic cancer stem cell motility
Kuc N, et al.
Biochemical Pharmacology, 156, 458-466 (2018)
Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.
Póngase en contacto con el Servicio técnico