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Key Documents

810241P

Avanti

TopFluor™ TMR PE

Avanti Research™ - A Croda Brand 810241P, powder

Sinónimos:

1-oleoyl-2-(6-((4,4-difluoro-1,3-dimethyl-5-(4-methoxyphenyl)-4-bora-3α,4α-diaza-s-indacene-2-propionyl)amino)hexanoyl)-sn-glycero-3- phosphoethanolamine

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About This Item

Fórmula empírica (notación de Hill):
C50H76 BF2N4 O10P
Número de CAS:
2260795-41-1
Peso molecular:
972.94
UNSPSC Code:
12352211
NACRES:
NA.25

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (810241P-1mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 810241P

shipped in

dry ice

storage temp.

−20°C

Categorías relacionadas

General description

Phosphoethanolamine contains a phosphate group linked with the second carbon of ethanolamine.

Biochem/physiol Actions

Phosphoethanolamine (PEA) is a precursor to phosphatidylethanolamine and phosphatidylcholine, involved in the biosynthesis of cell membrane. In human body, PEA is a product of degradation of sphingosine phosphate and endocannabinoid anandamide. PEA has potential cytotoxic properties and is known to induce the caspase-independent cell death. PEA is capable of inhibiting tumor growth in vitro and in vivo in mouse models.

Packaging

5 mL Amber Glass Screw Cap Vial (810241P-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Noam Pondé et al.
Ecancermedicalscience, 10, 681-681 (2016-12-03)
The use of unproven forms of therapy in cancer treatment is very common. In Brazil, the distribution by researchers to patients of an investigational agent called phophoethanolamine (PHOS) has led to a widely publicized scientific scandal. PHOS is a precursor
Ann C Kimble-Hill et al.
The journal of physical chemistry. B, 122(35), 8404-8415 (2018-06-08)
Phosphatidylinositol (PI) lipids are necessary for many cellular signaling pathways of membrane associated proteins, such as angiomotin (Amot). The Amot family regulates cellular polarity, growth, and migration. Given the low concentration of PI lipids in these membranes, it is likely
Dhaval Patel et al.
Oxidative medicine and cellular longevity, 2017, 4829180-4829180 (2017-08-09)
Phosphatidylethanolamine (PE) is the second most abundant phospholipid in mammalian cells. PE comprises about 15-25% of the total lipid in mammalian cells; it is enriched in the inner leaflet of membranes, and it is especially abundant in the inner mitochondrial

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