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Documentos clave

810110P

Avanti

12-NBD Stearate

Avanti Research™ - A Croda Brand 810110P, powder

Sinónimos:

12-N-methyl-(7-nitrobenz-2-oxa-1,3-diazo)aminostearic acid

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About This Item

Fórmula empírica (notación de Hill):
C25H40N4O5
Número de CAS:
117056-67-4
Peso molecular:
476.61
UNSPSC Code:
12352211
NACRES:
NA.25

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (810110P-1mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 810110P

shipped in

dry ice

storage temp.

−20°C

InChI

1S/C25H40N4O5/c1-3-4-5-12-15-20(16-13-10-8-6-7-9-11-14-17-23(30)31)28(2)21-18-19-22(29(32)33)25-24(21)26-34-27-25/h18-20H,3-17H2,1-2H3,(H,30,31)

InChI key

SAAVELCIPHKGJE-UHFFFAOYSA-N

General description

12-NBD Stearate is amphipathic, nonesterifiable fluorescent fatty acid probe and is a long-chain fatty acid (LCFA) derivative.

Application

12-NBD Stearate has been used in the fluorescent labeling of omega-3 fatty acid in biomaterial films and as a ligand for fatty acid binding protein 5 (FABP5) in competitive binding based high throughput fluorescence displacement assay. It may be used a ligand fluorescence displacement assay of fatty-acid binding protein 5 (FABP5).

Biochem/physiol Actions

12-NBD Stearate incorporated in lipid droplets and is used majorly in fluorescence displacement binding studies of fatty-acid binding proteins. The sterol carrier protein-2 (SCP-2) 15-kDa isoform favours NBD Stearate transport. The uptake of NBD Stearate is regulated by fatty acid binding protein (FABP) expression regulates uptake and inhibited by filipin III.

Packaging

5 mL Amber Glass Screw Cap Vial (810110P-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Faucher KM, et al.
Annals of Biomedical Engineering, 44(3), 782-792 (2016)
B P Atshaves et al.
The American journal of physiology, 274(3 Pt 1), C633-C644 (1998-04-08)
The effect of cellular differentiation on fatty acid uptake and intracellular diffusion was examined in transfected pluripotent mouse embryonic stem (ES) cells stably expressing intestinal fatty acid binding protein (I-FABP). Control ES cells, whether differentiated or undifferentiated, did not express
Gregory Carbonetti et al.
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