Saltar al contenido
MilliporeSigma
Todas las fotos(1)

Documentos clave

700094P

Avanti

cholestanol-d5

Avanti Research™ - A Croda Brand

Sinónimos:

111020

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
Todas las fotos(1)

About This Item

Fórmula empírica (notación de Hill):
C27H43D5O
Número de CAS:
2260669-14-3
Peso molecular:
393.70
UNSPSC Code:
12352211
NACRES:
NA.25

description

2,2,3,4,4-pentadeuterio-5α-cholestan-3β-ol

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (700094P-1mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand

shipped in

dry ice

storage temp.

−20°C

SMILES string

O[C@@]1(C([C@H]2[C@@]([C@@H]3[C@H]([C@H]4[C@@]([C@H](CC4)[C@@H](CCCC(C)C)C)(CC3)C)CC2)(CC1([2H])[2H])C)([2H])[2H])[2H]

General description

Cholestanol-d5 is a deuterated form of cholestanol. Cholestanol is a plant saturated sterol and has Δ5 double bond to the 5α position in the cholesterol structure and is a 5α-dihydro derivative of cholesterol.

Biochem/physiol Actions

Cholestanol deuterated has been administered in small intestine samples for the quantification of sterols by gas chromatography-mass spectrometry. The levels of cholesterol and cholestanol are elevated in tendons and brain in cerebrotendinous xanthomatosis due to the CYP27A1 (Cytochrome P450 Family 27 Subfamily A Member 1) deficiency. Cholestanol-d5 is useful as an internal standard to spike sediment samples for tandem mass spectrometry (MS/MS) for fecal sterol quantification. Cholestanol is a cholesterol absorption biomarker.

Packaging

5 mL Amber Glass Screw Cap Vial (700094P-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

Elija entre una de las versiones más recientes:

Certificados de análisis (COA)

Lot/Batch Number

Lo sentimos, en este momento no disponemos de COAs para este producto en línea.

Si necesita más asistencia, póngase en contacto con Atención al cliente

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

B P Lyons et al.
Marine pollution bulletin, 100(2), 689-698 (2015-08-01)
Microbial water quality and concentrations of faecal sterols in sediment have been used to assess the degree of sewage contamination in Kuwait's marine environment. A review of microbial (faecal coliform, faecal streptococci and Escherichia coli) water quality data identified temporal
Ann Båvner et al.
Journal of lipid research, 51(9), 2722-2730 (2010-06-01)
The rare disease cerebrotendinous xanthomatosis (CTX) is due to a lack of sterol 27-hydroxylase (CYP27A1) and is characterized by cholestanol-containing xanthomas in brain and tendons. Mice with the same defect do not develop xanthomas. The driving force in the development

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico