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MilliporeSigma

D188700

Sigma-Aldrich

N,N′-Dimethylthiourea

99%

Sinónimos:

1,3-Dimethyl-2-thiourea, 1,3-Dimethylisothiourea, Dimethylthiocarbamide

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About This Item

Fórmula lineal:
CH3NHCSNHCH3
Número de CAS:
Peso molecular:
104.17
Beilstein/REAXYS Number:
605454
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

assay

99%

form

crystals

SMILES string

CNC(=S)NC

InChI

1S/C3H8N2S/c1-4-3(6)5-2/h1-2H3,(H2,4,5,6)

InChI key

VLCDUOXHFNUCKK-UHFFFAOYSA-N

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General description

N,N′-Dimethylthiourea, also known as 1,3-Dimethylisothiourea, is commonly used in organic reactions to synthesize N-containing compounds such as N-acyl-substituted 1,1-diaminoethylenes, amidines, ureas, and thioureas. It also acts as a nucleophilic catalyst in the bromination of alcohols using N-bromosuccinimide (NBS), during the conversion to the corresponding bromides.

Application

  • Pharmaceutical Analysis: Mao et al. developed an itaconic acid-based organic-polymer monolithic column for hydrophilic capillary electrochromatography, which was used in pharmaceutical analysis. N,N′-Dimethylthiourea could be utilized to improve the column′s performance by acting as a potential organic modifier to enhance the separation processes (Mao et al., 2024).
  • Agricultural Research: Li et al. examined the effect of the reactive oxygen scavenger N,N′-Dimethylthiourea on seed germination and radicle elongation of maize. This research could help in understanding how this chemical can be used to influence plant growth under stress conditions, potentially improving agricultural productivity (Li et al., 2023).

pictograms

Exclamation mark

signalword

Warning

hcodes

pcodes

Hazard Classifications

Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


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