B4856
Diphenylmethanol
99%
Sinónimos:
Benzhydrol, Benzhydryl alcohol, Diphenyl carbinol
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About This Item
Fórmula lineal:
(C6H5)2CHOH
Número de CAS:
Peso molecular:
184.23
Beilstein/REAXYS Number:
1424379
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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Quality Level
assay
99%
form
powder
bp
297-298 °C (lit.)
mp
65-67 °C (lit.)
SMILES string
OC(c1ccccc1)c2ccccc2
InChI
1S/C13H12O/c14-13(11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10,13-14H
InChI key
QILSFLSDHQAZET-UHFFFAOYSA-N
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Application
Diphenylmethanol is used in the carbene-catalyzed dynamic kinetic resolution of α,α-disubstituted carboxylic esters. It can also be used in the chiral resolution of free-base and Ni(II) porphyrinoid complexes.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 2
ppe
dust mask type N95 (US), Eyeshields, Gloves
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In the present article, we have reported the design, synthesis, and identification of highly potent benzhydrol derivatives as squalene synthase inhibitors (compound 1). Unfortunately, the in vivo efficacies of the compounds were not enough for acquiring the clinical candidate. We
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Carbene-Catalyzed Dynamic Kinetic Resolution of Carboxylic Esters.
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Alkylation of alcohols for gas chromatographic analysis by a phase transfer catalysis technique. Evaluation of benzhydrol benzylation in a one-phase system.
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Acta pharmaceutica Suecica, 16(4), 247-262 (1979-01-01)
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