931853

SPhos Pd G6 acylation

≥95%

• Sinónimos: (SPhos)Pd(4-CH₂CH₂CONHSPh)Br
• Fórmula empírica (notación de Hill): C₃₉H₄₇BrNO₆PPd
• Número de CAS: 2723495-97-2
• Peso molecular: 843.09
• MDL number: MFCD34704619
• UNSPSC Code: 12352100
• NACRES: NA.21

Propiedades

• Quality Level: 100
• assay: ≥95%
• form: powder
• reaction suitability: reagent type: catalyst; reaction type: Cross Couplings
• greener alternative product characteristics: Catalysis; Learn more about the Principles of Green Chemistry.
• sustainability: Greener Alternative Product
• greener alternative category: Aligned

Descripción

General description

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. This product has been enhanced for catalytic efficiency. Click here for more information.

Application

SPhos Pd G6 acylation is an oxidative addition complex (OAC) of SPhos for use in bioconjugation. The pendant NHS-functional group allows coupling to protein amines through a selective acylation. The protein-OAC can then be reacted with a second, cysteine-containing protein. This facile approach allows for protein homodimerization as well as the formation of antibody-protein conjugates.

Learn more about G6 Buchwald precatalysts

Other Notes

Palladium–Protein Oxidative Addition Complexes by Amine-Selective Acylation

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable