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MilliporeSigma

914800

Sigma-Aldrich

Hyaluronic acid methacrylate

Degree of substitution: 10% - 30%, Mw 170,000-250,000

Sinónimos:

HA MA, HA methacrlate, Hyaluronic acid MA, Hyaluronic acid methacrlate high mol. weight

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About This Item

Fórmula lineal:
(NaC20H28NO15)n
UNSPSC Code:
12352106
NACRES:
NA.23

Quality Level

description

NMR: Conforms to structure

form

(powder or chunk(s) or fibers)

mol wt

Mw 170,000-250,000

color

white to off-white

storage temp.

2-8°C

Application

Hyaluronic acid (HA) is a linear polysaccharide of alternating D-glucuronic acid and N-acetyl-D-glucosamine found primarily in connective tissues. HA based hydrogels are widely used in tissue engineering, 3D bioprinting, and drug deliery applications. The methacrylate functionalized hyaluronic acid is photo-crosslinkable, and can be used to generate crosslinked hydrogels.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Cindy Chung et al.
Tissue engineering. Part A, 15(2), 243-254 (2009-02-06)
Mesenchymal stem cells (MSCs) are multipotent progenitor cells whose plasticity and self-renewal capacity have generated significant interest for applications in tissue engineering. The objective of this study was to investigate MSC chondrogenesis in photo-cross-linked hyaluronic acid (HA) hydrogels. Because HA
Judy Yeh et al.
Biomaterials, 27(31), 5391-5398 (2006-07-11)
Encapsulation of mammalian cells within hydrogels has great utility for a variety of applications ranging from tissue engineering to cell-based assays. In this work, we present a technique to encapsulate live cells in three-dimensional (3D) microscale hydrogels (microgels) of controlled
Aleksander Skardal et al.
Tissue engineering. Part A, 16(8), 2675-2685 (2010-04-15)
Bioprinting by the codeposition of cells and biomaterials is constrained by the availability of printable materials. Herein we describe a novel macromonomer, a new two-step photocrosslinking strategy, and the use of a simple rapid prototyping system to print a proof-of-concept

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