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908630

Sigma-Aldrich

Poly(lactide-co-glycolide)-Flamma Fluor near-IR

lactide:glycolide (50:50), Mn 20,000-30,000

Sinónimos:

PLGA near IR, PLGA-FPI749, near IR conjugated PLGA

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About This Item

Fórmula lineal:
(C3H4O2)x(C2H2O2)y
UNSPSC Code:
12162002
NACRES:
NA.23

form

powder or chunks

feed ratio

lactide:glycolide (50:50)

mol wt

Mn 20,000-30,000
average Mn 20,000-30,000

composition

Dye Content, 7.54 μg/mg (polymer)

color

blue to teal

storage temp.

−20°C

Application

Poly(lactide-co-glycolide)-Flamma Fluor near-IR is labelled with Flamma Fluor FPI749 near-IR dye. It can be used in the formation of fluoresent nanoparticles for in-vivo imaging applications.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Fanfei Meng et al.
ACS nano, 12(7), 6458-6468 (2018-06-20)
Fluorescence-based whole-body imaging is widely used in the evaluation of nanoparticles (NPs) in small animals, often combined with quantitative analysis to indicate their spatiotemporal distribution following systemic administration. An underlying assumption is that the fluorescence label represents NPs and the
Yihan Xu et al.
Journal of biomedical materials research. Part B, Applied biomaterials, 105(6), 1692-1716 (2016-04-22)
Poly (lactic-co-glycolic acid) (PLGA) copolymers have been broadly used in controlled drug release applications. Because these polymers are biodegradable, they provide an attractive option for drug delivery vehicles. There are a variety of material, processing, and physiological factors that impact
R Gref et al.
Science (New York, N.Y.), 263(5153), 1600-1603 (1994-03-18)
Injectable nanoparticulate carriers have important potential applications such as site-specific drug delivery or medical imaging. Conventional carriers, however, cannot generally be used because they are eliminated by the reticulo-endothelial system within seconds or minutes after intravenous injection. To address these

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