900757

Sodium pyridine-2-sulfinate

• Sinónimos: 2-Pyridinesulfinic acid, Sodium salt, Willis 2-pyridylsulfinates H
• Fórmula empírica (notación de Hill): C₅H₄NNaO₂S
• Número de CAS: 24367-66-6
• Peso molecular: 165.15
• UNSPSC Code: 12352101
• NACRES: NA.22

Propiedades

• form: powder or crystals
• Quality Level: 100
• reaction suitability: reaction type: C-C Bond Formation
• mp: 292 °C
• functional group: sulfinic acid
• InChI: 1S/C5H5NO2S.Na/c7-9(8)5-3-1-2-4-6-5;/h1-4H,(H,7,8);/q;+1/p-1
• InChI key: HQCGASCBCQJRDJ-UHFFFAOYSA-M

Descripción

Application

This 2-pyridylsulfinate enables Suzuki-Miyaura cross coupling with aryl halides to access diverse pyridine derivatives as reported by the laboratory of Michael Willis.. No longer impeded by unstable 2-pyridyl boronates, the sulfinate alternatives provide Pd-catalyzed coupling routes to therapeutically valuable pyridine rings.

Other Notes

• Technology Spotlight: Willis Pyridinates for Palladium-Catalyzed Cross-Coupling Reactions.
• Pyridine Sulfinates as General Nucleophilic Coupling Partners in Palladium-Catalyzed Cross-Coupling Reactions with Aryl Halides

Información de seguridad

• pictograms: GHS05
• signalword: Danger
• hcodes: H314
• pcodes: P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363
• Hazard Classifications: Eye Dam. 1 - Skin Corr. 1B
• Storage Class: 8A - Combustible corrosive hazardous materials
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable