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MilliporeSigma

552151

Sigma-Aldrich

D-Glucose-13C6,1,2,3,4,5,6,6-d7

97 atom % D, 99 atom % 13C

Sinónimos:

Deuterated Glucose, Labeled Glucose, D-Glucose-13C6,C-d7, Dextrose-13C6,C-d7

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About This Item

Fórmula empírica (notación de Hill):
13C6H5D7O6
Número de CAS:
Peso molecular:
193.15
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.12

isotopic purity

99 atom % 13C
97 atom % D

Quality Level

assay

99% (CP)

form

powder

optical activity

[α]25/D +52.0°, c = 2 in H2O (trace NH4OH)

technique(s)

bio NMR: suitable
protein expression: suitable

mp

150-152 °C (lit.)

mass shift

M+13

SMILES string

[2H][13C](=O)[13C@]([2H])(O)[13C@@]([2H])(O)[13C@]([2H])(O)[13C@]([2H])(O)[13C]([2H])([2H])O

InChI

1S/C6H12O6/c7-1-3(9)5(11)6(12)4(10)2-8/h1,3-6,8-12H,2H2/t3-,4+,5+,6+/m0/s1/i1+1D,2+1D2,3+1D,4+1D,5+1D,6+1D

InChI key

GZCGUPFRVQAUEE-VVZLUFAVSA-N

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General description

D- Glucose is a monosaccharide (simple sugar). It is a vital source of energy for living organisms. It exists in a cyclic form, containing six carbon atoms. It is present naturally in all plants and fruits in free or bound state. It is synthesized by the process, gluconeogenesis, in the liver and kidney.

Biochem/physiol Actions

D-Glucose is involved in the metabolic processes, such as glycolysis and Kreb′s cycle for the generation of adenosine triphosphates. It is stored in the form of glycogen in liver. D-Glucose moieties constitutes to form cellulose by β-1,4-glycosidic linkage.

Packaging

This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificados de análisis (COA)

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Hydrolysis of cellulose to glucose by solid acid catalysts
Huang YB and Fu Y
Green Chemistry, 15(5), 1095-1111 (2013)
Carl Öster et al.
Science advances, 5(7), eaaw6756-eaaw6756 (2019-08-09)
Ion conduction through potassium channels is a fundamental process of life. On the basis of crystallographic data, it was originally proposed that potassium ions and water molecules are transported through the selectivity filter in an alternating arrangement, suggesting a "water-mediated"
Chaevien S Clendinen et al.
Analytical chemistry, 87(11), 5698-5706 (2015-05-02)
The many advantages of (13)C NMR are often overshadowed by its intrinsically low sensitivity. Given that carbon makes up the backbone of most biologically relevant molecules, (13)C NMR offers a straightforward measurement of these compounds. Two-dimensional (13)C-(13)C correlation experiments like
Shilpa Nargund et al.
Biotechnology progress, 31(5), 1179-1186 (2015-06-23)
(13)C-metabolic flux analysis was used to understand copper deficiency-related restructuring of energy metabolism, which leads to excessive lactate production in recombinant protein-producing CHO cells. Stationary-phase labeling experiments with U-(13)C glucose were conducted on CHO cells grown under high and limiting
Soumya P Behera et al.
Nature communications, 11(1), 5547-5547 (2020-11-05)
Methyl-NMR enables atomic-resolution studies of structure and dynamics of large proteins in solution. However, resonance assignment remains challenging. The problem is to combine existing structural informational with sparse distance restraints and search for the most compatible assignment among the permutations.

Artículos

Our company presents an informative page regarding the use of ISOTEC Stable Isotopes to Amplify Recombinant Protein Expression with ISOGRO.

Utilizing ISOGRO® Supplementation of M9 Minimal Media to Enhance Recombinant Protein Expression.

Solid-state NMR on Larger Biomolecules; Sigma-Aldrich.com

Learn about monosaccharide biosynthesis and the metabolism of monosaccharides. A unit of a carbohydrate and the simplest form of a sugar, a monosaccharide cannot be hydrolyzed into a simpler compound.

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La estructura de las proteínas proporciona información valiosa que puede utilizarse para inferir la función de la proteína. El estudio de la estructura de las proteínas y la cartografía de las interacciones proteicas, los niveles de expresión y su ubicación permiten la identificación de biomarcadores de enfermedad y posibles dianas farmacológicas para el tratamiento terapéutico.

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