540838

4-Piperidine butyric acid hydrochloride

97%

• Sinónimos: 4-(Piperidin-4-yl)butanoic acid hydrochloride
• Fórmula empírica (notación de Hill): C₉H₁₈ClNO₂
• Número de CAS: 84512-08-3
• Peso molecular: 207.70
• MDL number: MFCD02684340
• UNSPSC Code: 12352100
• PubChem Substance ID: 24878498
• NACRES: NA.22

Propiedades

• Quality Level: 100
• assay: 97%
• mp: 113-117 °C (lit.)
• functional group: carboxylic acid
• SMILES string: Cl[H].OC(=O)CCCC1CCNCC1
• InChI: 1S/C9H17NO2.ClH/c11-9(12)3-1-2-8-4-6-10-7-5-8;/h8,10H,1-7H2,(H,11,12);1H
• InChI key: UTPNREIRALGKPW-UHFFFAOYSA-N

Descripción

General description

4-Piperidine butyric acid hydrochloride participates in the synthesis of FK866 [(E)-N-[4-(1-benzoylpiperidin-4-yl)butyl]-3-(pyridin-3-yl)acrylamide], an inhibitor of NAD biosynthesis.

Application

Reactant for:
Modification of 3-amidinophenylalanine-derived matriptase inhibitors
Reactions between Weinreb amides and 2-magnesiated oxazoles

Reactant for synthesis of:
NAmPRTase inhibitors
FK866 analogs for NAD salvage inhibition

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H302,H315,H319,H335
• pcodes: P261 - P264 - P271 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 2
• flash_point_f: 210.2 °F - closed cup
• flash_point_c: 99 °C - closed cup
• ppe: dust mask type N95 (US), Eyeshields, Gloves