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MilliporeSigma

477567

Sigma-Aldrich

5,10,15,20-Tetrakis(4-hydroxyphenyl)-21H,23H-porphine

Dye content 95 %

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About This Item

Fórmula empírica (notación de Hill):
C44H30N4O4
Número de CAS:
Peso molecular:
678.73
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47

form

powder

Quality Level

composition

Dye content, 95%

mp

>300 °C (lit.)

λmax

421 nm

ε (extinction coefficient)

≥285000 at 417-423 nm in methanol at 0.001 g/L

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

Oc1ccc(cc1)-c2c3ccc(n3)c(-c4ccc(O)cc4)c5ccc([nH]5)c(-c6ccc(O)cc6)c7ccc(n7)c(-c8ccc(O)cc8)c9ccc2[nH]9

InChI

1S/C44H30N4O4/c49-29-9-1-25(2-10-29)41-33-17-19-35(45-33)42(26-3-11-30(50)12-4-26)37-21-23-39(47-37)44(28-7-15-32(52)16-8-28)40-24-22-38(48-40)43(36-20-18-34(41)46-36)27-5-13-31(51)14-6-27/h1-24,45,48-52H/b41-33-,41-34-,42-35-,42-37-,43-36-,43-38-,44-39-,44-40-

InChI key

VFHDWGAEEDVVPD-LWQDQPMZSA-N

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General description

5,10,15,20-Tetrakis(4-hydroxyphenyl)-21H,23H-porphine (TPPOH, 2H-OHTPP) is an achiral porphyrin derivative.

Application

It may be used to prepare porphyrin based matrices for the detection of water soluble vitamins by matrix-assisted laser desorption/ionization (MALDI) mass spectrometry. It may be used to prepare 5,10,15,20-tetrakis (4-polyethyleneoxy)phenyl)) porphyrin. Nanoporous silica inserted with 2H-OHTPP imparts gas sensitivity, and it could be useful to detect NO2 by surface plasmon resonance.

pictograms

CorrosionExclamation mark

signalword

Danger

hcodes

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1A - STOT SE 3

target_organs

Respiratory system

Storage Class

8A - Combustible corrosive hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Detection of water?soluble vitamins by matrix?assisted laser desorption/ionization time?of?flight mass spectrometry using porphyrin matrices.
Chen YT and Ling YC
Journal of Mass Spectrometry : Jms, 37(7), 716-730 (2002)
Prunier ML
Catalysis of Organic Reactions null
Anna Synak et al.
The journal of physical chemistry. B, 114(49), 16567-16573 (2010-11-26)
The relaxation dynamics of 5,10,15,20-tetrakis(4-hydroxyphenyl)-porphyrin (p-THPP) in tetrahydrofuran (THF) and encapsulated within the human serum albumin (HSA) protein in water solution was investigated. The protein environment affects the B→Q(y) and Q(x)→Q(y) transition dynamics (from 80 and 140-200 fs in THF
Giovanna De Luca et al.
The journal of physical chemistry. B, 110(29), 14135-14141 (2006-07-21)
Acidification of tetrakis(4-hydroxyphenyl)porphyrin (THPP) and tetrakis(3,5-dihydroxyphenyl)porphyrin (OHPP) in dichloromethane solutions has been investigated as a function of the nature of the counteranion. These porphyrins exhibit different patterns of behavior, and extended aggregates are formed displaying broad extinction features together with
Yvette Niamien Konan et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 18(3-4), 241-249 (2003-03-28)
A photosensitizer, meso-tetra(hydroxyphenyl)porphyrin (p-THPP) was incorporated into sterile submicronic nanoparticles of poly(D,L-lactide-co-glycolide) (50:50 and 75:25 PLGA) and poly(D,L-lactide) (PLA). With all polymers used, sub-130 nm p-THPP-loaded nanoparticles with similar drug loadings and entrapment efficiencies were produced using the emulsification-diffusion technique.

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