333662

1H-1,2,3-Triazole

97%

• Sinónimos: 2,3-Diazapyrrole, 2H-1,2,3-Triazole, Osotriazole, Pyrrodiazole, Triazacyclopentadiene
• Fórmula empírica (notación de Hill): C₂H₃N₃
• Número de CAS: 288-36-8
• Peso molecular: 69.07
• MDL number: MFCD00014490
• UNSPSC Code: 12352100
• PubChem Substance ID: 24860165
• NACRES: NA.22

Propiedades

• assay: 97%
• form: liquid
• refractive index: n20/D 1.498 (lit.)
• bp: 203 °C/752 mmHg (lit.)
• mp: 23-25 °C (lit.)
• density: 1.192 g/mL at 25 °C (lit.)
• SMILES string: c1c[nH]nn1
• InChI: 1S/C2H3N3/c1-2-4-5-3-1/h1-2H,(H,3,4,5)
• InChI key: QWENRTYMTSOGBR-UHFFFAOYSA-N

Descripción

General description

2H-1,2,3-triazole is tautomeric form of 1H-1,2,3-triazole. 1H-1,2,3-triazole effectively promotes the proton conduction in polymer electrolyte membranes via an intermolecular proton-transfer mechanism.

Application

• Crystalline framework materials: Research on triazole carboxylic acid ligand has demonstrated its application in smart crystalline framework materials, notably for fluorescence sensing and catalytic reduction of p-nitrophenol, illustrating its utility in chemical sensing and environmental applications (Lv et al., 2023).
• PXR receptor modulation: 1H-1,2,3-Triazole-4-carboxamides have been optimized as potent and selective inverse agonists and antagonists of the PXR receptor, providing insights into the design of receptor-specific drugs (Li et al., 2022).
• Large-scale synthesis: The large-scale synthesis of a Notum inhibitor employing a modified Sakai reaction illustrates the importance of 1H-1,2,3-triazole in the production of biochemical reagents, which can be essential in medical research and drug development (Atkinson et al., 2022).

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3
• flash_point_f: 224.6 °F - closed cup
• flash_point_c: 107 °C - closed cup
• ppe: Eyeshields, Gloves, type ABEK (EN14387) respirator filter