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320684

Sigma-Aldrich

3,3′-Diethyloxacarbocyanine iodide

98%

Sinónimos:

DiOC2(3)

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About This Item

Fórmula empírica (notación de Hill):
C21H21IN2O2
Número de CAS:
905-96-4
Peso molecular:
460.31
EC Number:
212-996-6
MDL number:
MFCD00011952
UNSPSC Code:
12352103
PubChem Substance ID:
57648658
NACRES:
NA.23

Quality Level

100

assay

98%

form

solid

mp

278 °C (dec.) (lit.)

λmax

483 nm

SMILES string

[I-].CCN1\C(Oc2ccccc12)=C\C=C\c3oc4ccccc4[n+]3CC

InChI

1S/C21H21N2O2.HI/c1-3-22-16-10-5-7-12-18(16)24-20(22)14-9-15-21-23(4-2)17-11-6-8-13-19(17)25-21;/h5-15H,3-4H2,1-2H3;1H/q+1;/p-1

InChI key

FIZZUEJIOKEFFZ-UHFFFAOYSA-M

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General description

3,3′-Diethyloxacarbocyanine iodide(DiOC) is a cyanine based dye which is used in the photosensitization of mitochondria and endoplastic recticulum in animals and plant cells.

Application

DiOC may be used as a conjugate for labelling cells for cytofluorometry studies . It may also be used in the imaging of carbon nanotubes(CNTs) using fluorescence microscopy. Staining of spermatozoa can potentially be done by DiOC which can be used in flow cytometric measurement and viability assay.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificados de análisis (COA)

Lot/Batch Number
SHBM9483
SHBM8824
SHBM6153
MKCD8585
MKBS2626V

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Photosensitization by 3, 3?-dihexyloxacarbocyanine iodide: specific disruption of microtubules and inactivation of organelle motility.
Lee C, et al.
Cancer Research, 55(10), 2063-2069 (1995)
Sheng-Chieh Wang et al.
International journal of molecular sciences, 21(17) (2020-09-10)
The sensitizing effect of chromone-derived compounds on UVC-induced proliferation inhibition has not been comprehensively investigated so far. The subject of this study was to examine the proliferation change of oral cancer cells while using the combined treatment of UVC (254
Issues in Chemical Engineering and other Chemistry Specialties (2011)
The functionality of mitochondria differentiates human spermatozoa with high and low fertilizing capability.
Gallon F, et al.
Fertility and Sterility, 86(5), 1526-1530 (2006)
Visualization of individual carbon nanotubes with fluorescence microscopy using conventional fluorophores.
Prakash R, et al.
Applied Physics Letters, 83(6), 1219-1221 (2003)
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