270245

4-Methoxybenzyl chloride

contains potassium carbonate as stabilizer, 98%

• Sinónimos: 4-(Chloromethyl)anisole
• Fórmula lineal: CH₃OC₆H₄CH₂Cl
• Número de CAS: 824-94-2
• Peso molecular: 156.61
• Beilstein/REAXYS Number: 606667
• EC Number: 212-540-6
• MDL number: MFCD00000915
• UNSPSC Code: 12352100
• PubChem Substance ID: 24856365
• NACRES: NA.22

Propiedades

• assay: 98%
• form: liquid
• contains: potassium carbonate as stabilizer
• refractive index: n20/D 1.548 (lit.)
• bp: 117-118 °C/14 mmHg (lit.)
• mp: −1 °C (lit.)
• density: 1.155 g/mL at 25 °C (lit.)
• storage temp.: 2-8°C
• SMILES string: COc1ccc(CCl)cc1
• InChI: 1S/C8H9ClO/c1-10-8-4-2-7(6-9)3-5-8/h2-5H,6H2,1H3
• InChI key: MOHYOXXOKFQHDC-UHFFFAOYSA-N

Descripción

General description

4-Methoxybenzyl chloride undergoes mild oxidative claevage with ceric ammonium nitrate.

Application

4-Methoxybenzyl chloride was used to benzylate the aniline nitrogen. It was also used in the synthesis of 1-naphthamide and diarymethanes via Suzuki cross-coupling with postassium aryltrifluoroborates.

O/N protecting group reagent which can be mildly oxidatively cleaved, e.g., with ceric ammonium nitrate.

Información de seguridad

• pictograms: GHS05
• signalword: Danger
• hcodes: H314
• pcodes: P280 - P301 + P330 + P331 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Skin Corr. 1B
• Storage Class: 8A - Combustible corrosive hazardous materials
• wgk_germany: WGK 3
• flash_point_f: 228.2 °F - closed cup
• flash_point_c: 109 °C - closed cup
• ppe: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter