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MilliporeSigma

253103

Sigma-Aldrich

29H,31H-Phthalocyanine

β-form, 98%

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About This Item

Fórmula empírica (notación de Hill):
C32H18N8
Número de CAS:
Peso molecular:
514.54
Beilstein/REAXYS Number:
378323
EC Number:
MDL number:
UNSPSC Code:
12352103
PubChem Substance ID:
NACRES:
NA.23

assay

98%

form

powder

mp

>300 °C (dec.) (lit.)

λmax

698 nm

SMILES string

c1ccc2c3nc(nc4[nH]c(nc5nc(nc6[nH]c(n3)c7ccccc67)c8ccccc58)c9ccccc49)c2c1

InChI

1S/C32H18N8/c1-2-10-18-17(9-1)25-33-26(18)38-28-21-13-5-6-14-22(21)30(35-28)40-32-24-16-8-7-15-23(24)31(36-32)39-29-20-12-4-3-11-19(20)27(34-29)37-25/h1-16H,(H2,33,34,35,36,37,38,39,40)

InChI key

IEQIEDJGQAUEQZ-UHFFFAOYSA-N

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Application

Suitable as laser dye

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Qinggong Tang et al.
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As a novel low-side-effect cancer therapy, photo-immunotherapy (PIT) is based on conjugating monoclonal antibody (mAb) with a near-infrared (NIR) phthalocyanine dye IRDye700DX (IR 700). IR700 is not only fluorescent to be used as an imaging agent, but also phototoxic. When
A Atxabal et al.
Nature communications, 7, 13751-13751 (2016-12-13)
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Molecular pharmaceutics, 15(9), 3634-3641 (2018-02-17)
Near infrared photoimmunotherapy (NIR-PIT) is a new target-cell-specific cancer treatment that induces highly selective necrotic/immunogenic cell death after systemic administration of a photoabsorber antibody conjugate and subsequent NIR light exposure. However, the depth of NIR light penetration in tissue (approximately
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Near infrared photoimmunotherapy (NIR-PIT) is a newly developed and highly selective cancer treatment that induces necrotic/immunogenic cell death. It employs a monoclonal antibody (mAb) conjugated to a photo-absorber dye, IRDye700DX, which is activated by NIR light. Tumor-targeting NIR-PIT is also
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