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Documentos

198781

Sigma-Aldrich

12-Hydroxydodecanoic acid

97%

Sinónimos:

12-Hydroxylauric acid

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About This Item

Fórmula lineal:
HO(CH2)11COOH
Número de CAS:
505-95-3
Peso molecular:
216.32
Beilstein/REAXYS Number:
1238370
EC Number:
208-025-0
MDL number:
MFCD00002739
UNSPSC Code:
12352100
PubChem Substance ID:
24851879
NACRES:
NA.22

assay

97%

mp

85-88 °C (lit.)

SMILES string

OCCCCCCCCCCCC(O)=O

InChI

1S/C12H24O3/c13-11-9-7-5-3-1-2-4-6-8-10-12(14)15/h13H,1-11H2,(H,14,15)

InChI key

ZDHCZVWCTKTBRY-UHFFFAOYSA-N

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Application

12-Hydroxydodecanoic acid was used in the synthesis of high molecular weight poly[(12-hydroxydodecanoate)-co-(12-hydroxystearate)] [poly(12HD-co-12HS)] samples with variable monomer ratios using methyl 12-hydroxystearate.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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H A Dirven et al.
Journal of chromatography, 564(1), 266-271 (1991-03-08)
The formation of omega-hydroxylauric acid from lauric acid is an indicator of the activity of cytochrome P-450 IV family proteins. The two main metabolites of lauric acid, (omega-1)-and omega-hydroxylauric acid, have been completely separated by reversed-phase high-performance liquid chromatography. Measurement
P Jezek et al.
FEBS letters, 408(2), 166-170 (1997-05-19)
Fatty acid (FA) uniport via mitochondrial uncoupling protein (UcP) was detected fluorometrically with PBFI, potassium-binding benzofuran phthalate and SPQ, 6-methoxy-N-(3-sulfopropyl)-quinolinium, indicating K+ and H+, respectively. The FA structural patterns required for FA flip-flop, UcP-mediated FA uniport, activation of UcP-mediated H+
D D Giera et al.
Fundamental and applied toxicology : official journal of the Society of Toxicology, 16(2), 348-355 (1991-02-01)
Assessment of hepatic omega-oxidation of fatty acids by cytochrome P450IV enzymes in toxicology studies can be a means of evaluating test compound effects on peroxisomal proliferation. Routine assay of omega-oxidation, however, requires a simpler method of enzymatic analysis than currently
Elena Bailo et al.
Analytical and bioanalytical chemistry, 394(7), 1797-1801 (2009-06-16)
Surface-enhanced Raman scattering was used as a spectroscopic tool to investigate the changes brought upon cytochrome P450BSss after fatty acid binding. Differences in the spectra of substrate-free and substrate-bound enzyme were observed indicating the potential for this method to be
Junjun Wang et al.
International journal of molecular sciences, 19(3) (2018-03-15)
This study was aimed to clarify the effect of honokiol (Hon) on the activity of Cytochrome P450 (CYP450) enzymes, and the level of mRNA expression of liver and kidney transporters in type 2 diabetic rats induced by high-fat diet and
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