194905

12-Crown-4

98%

• Sinónimos: 1,4,7,10-Tetraoxacyclododecane
• Fórmula empírica (notación de Hill): C₈H₁₆O₄
• Número de CAS: 294-93-9
• Peso molecular: 176.21
• Beilstein/REAXYS Number: 1363064
• EC Number: 206-036-5
• MDL number: MFCD00005103
• UNSPSC Code: 12352005
• PubChem Substance ID: 24851661
• NACRES: NA.22

Propiedades

• Quality Level: 100
• assay: 98%
• form: liquid
• refractive index: n20/D 1.463 (lit.)
• bp: 61-70 °C/0.5 mmHg (lit.)
• mp: 16 °C (lit.)
• density: 1.089 g/mL at 25 °C (lit.)
• functional group: ether
• SMILES string: C1COCCOCCOCCO1
• InChI: 1S/C8H16O4/c1-2-10-5-6-12-8-7-11-4-3-9-1/h1-8H2
• InChI key: XQQZRZQVBFHBHL-UHFFFAOYSA-N

Descripción

General description

12-Crown-4 is a crown ether generally used as a ligand in coordination chemistry. It is also known as lithium ionophore because of its strong chelating property specific to lithium cation.

Application

12-Crown-4 can be used as:

• A promoter in the synthesis of poly(diethylsiloxane) (PDES) from monomer hexaethylcyclotrisiloxane using NaOH as a catalyst via anionic ring-opening polymerization.
• As an additive in the preparation of triarylmethane derivatives by palladium-catalyzed cross coupling reaction of aryl bromides with diarylmethane derivatives.
• A phase transfer catalyst in organic synthesis.

Información de seguridad

• pictograms: GHS06
• signalword: Danger
• hcodes: H330
• pcodes: P260 - P271 - P284 - P304 + P340 + P310 - P403 + P233 - P405
• Hazard Classifications: Acute Tox. 1 Inhalation
• Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk_germany: WGK 3
• flash_point_f: 235.4 °F - closed cup
• flash_point_c: 113 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter