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MilliporeSigma

194484

Sigma-Aldrich

O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride

≥98%

Sinónimos:

PFBHA·HCl

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About This Item

Fórmula lineal:
C6F5CH2ONH2·HCl
Número de CAS:
Peso molecular:
249.57
Beilstein/REAXYS Number:
4031190
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

≥98%

form

solid

mp

227 °C (subl.) (lit.)

solubility

water: soluble 50 mg/mL, clear to slightly hazy, colorless

functional group

fluoro

SMILES string

Cl.NOCc1c(F)c(F)c(F)c(F)c1F

InChI

1S/C7H4F5NO.ClH/c8-3-2(1-14-13)4(9)6(11)7(12)5(3)10;/h1,13H2;1H

InChI key

HVMVKNXIMUCYJA-UHFFFAOYSA-N

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Application

O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride is used:
  • In the preparation of oximes of steroids-bearing keto group.
  • As a derivatization reagent in the determination of thromboxane B2, prostaglandins, amygdalin, and a variety of aldehydes, ketones, and acids.
It is a versatile reagent used for the detection of carbonyl-containing compounds by GC, GC-MS, and other methods.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Raya Ahmed et al.
Cell reports, 33(11), 108501-108501 (2020-12-17)
A central paradigm in the field of lymphocyte biology asserts that replicatively senescent memory T cells express the carbohydrate epitope CD57. These cells nonetheless accumulate with age and expand numerically in response to persistent antigenic stimulation. Here, we use in vivo deuterium
Vicente Ferreira et al.
Journal of chromatography. A, 1122(1-2), 255-265 (2006-05-20)
This work presents a thorough study of some aspects critical to the quantitative performance of methods for the determination of volatile aldehydes previously derivatized to pentafluorobenzyl hydroxylamine oximes. The conclusions of the study are further applied to the validation of
Chunhui Deng et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 810(2), 269-275 (2004-09-24)
Analysis of breath acetone has been used as a diagnostic tool for diabetes. Due to its nature of volatility and activity, it is very difficult to accurately measure the concentration of acetone in human breath by gas chromatography-mass spectrometry (GC-MS).
Yun-Gon Kim et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 893-894, 177-181 (2012-03-31)
Nucleotide diphosphate (NDP) sugars are widely present in antibiotics and glycoconjugates, such as protein- and lipid-linked oligosaccharides, where they act as substrates for glycosyltransferase in eukaryotes and prokaryotes. Among NDP sugars, NDP-4-keto sugars are key intermediates in the synthesis of
S W Liou et al.
Bulletin of environmental contamination and toxicology, 80(4), 324-328 (2008-03-18)
This work studied the feasibility of using a solid phase microextraction (SPME) fiber for sampling and analysis of gaseous formaldehyde as well as particulate-bound formaldehyde from burning Chinese incense. The SPME fiber with PDMS/DVB coating were partially coated with o-(2,3,4,5,6-pentafluorobenzyl)-hydroxylamine

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