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188840

Sigma-Aldrich

Ethyl acetimidate hydrochloride

97%

Sinónimos:

Ethyl acetoamidate hydrochloride, Ethyl acetocarboximidate hydrochloride, Ethyl acetoimidate hydrochloride, Ethyl ethanimidate hydrochloride, Ethyl ethanimidoate hydrochloride, Ethyl iminoacetate hydrochloride

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About This Item

Fórmula lineal:
CH3C(=NH)OC2H5 · HCl
Número de CAS:
2208-07-3
Peso molecular:
123.58
Beilstein/REAXYS Number:
3552401
EC Number:
218-631-7
MDL number:
MFCD00012572
UNSPSC Code:
12352100
PubChem Substance ID:
24851324
NACRES:
NA.22

Quality Level

100

assay

97%

mp

112-114 °C (lit.)

solubility

water: soluble 50 mg/mL, clear, colorless

functional group

amine

SMILES string

Cl.CCOC(C)=N

InChI

1S/C4H9NO.ClH/c1-3-6-4(2)5;/h5H,3H2,1-2H3;1H

InChI key

WGMHMVLZFAJNOT-UHFFFAOYSA-N

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Application

Ethyl acetimidate hydrochloride was used in preparation of amidinated carbonic anhydrase via chemical modification of human erythrocyte carbonic anhydrase. It was also used in synthesis of methyl 2-methyl-2-thiazoline-4-carboxylate hydrochloride.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificados de análisis (COA)

Lot/Batch Number
BCBK9192V
BCBB1741
BCBB1739
BCBB1739V
BCBB1740

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Inhibition and chemical modifications of human erythrocyte carbonic anhydrase B.
P L Whitney et al.
The Journal of biological chemistry, 242(18), 4212-4220 (1967-09-25)
2-Methyl-2-thiazoline-4-carboxylic acid: formation from N-acetylcysteine and hydrolysis.
SMITH HA and GORIN G.
The Journal of Organic Chemistry, 26(3), 820-823 (1961)
P de la Llosa et al.
FEBS letters, 191(2), 211-215 (1985-10-28)
The lactogenic activity (L.A.) of oPRL and hGH derivatives obtained by chemical modifications of lysine residues was studied by radioreceptor assay. Control treatment with borohydride had a slight effect on the L.A. of hGH but drastically reduced the oPRL activity;
J A Kauffman et al.
Toxicology and applied pharmacology, 79(2), 211-217 (1985-06-30)
Blockade of neuromuscular transmission was produced in the lower hind limb of the rat by local injection of either type A or type F botulinum toxin (BoTx). At 1, 3, 7, and 10 days after injection, the extensor digitorum longus
W M Keung et al.
International journal of peptide and protein research, 42(6), 504-508 (1993-12-01)
Lysine and arginine residues in trichosanthin were modified with ethyl acetimidate and phenylglyoxal, respectively. The effects of these chemical modifications on the cell-free protein-synthesis-inhibitory activity and the antigen-antibody (Ag-Ab) interaction between trichosanthin and its antibody were examined. Ethyl acetimidate modification
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