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Key Documents

Otros documentos

167134

Sigma-Aldrich

Bromohydroquinone

97%

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About This Item

Fórmula lineal:
BrC6H3(OH)2
Número de CAS:
583-69-7
Peso molecular:
189.01
EC Number:
209-516-2
MDL number:
MFCD00041747
UNSPSC Code:
12352100
PubChem Substance ID:
24850194
NACRES:
NA.22

assay

97%

mp

112-116 °C (lit.)

SMILES string

Oc1ccc(O)c(Br)c1

InChI

1S/C6H5BrO2/c7-5-3-4(8)1-2-6(5)9/h1-3,8-9H

InChI key

REFDOIWRJDGBHY-UHFFFAOYSA-N

Categorías relacionadas

Application

Bromohydroquinone was used in the synthesis of Π-conjugated polymers composed of alkyl carbazole/dialkoxyphenylene and squaraine units via Sonogashira cross-coupling reactions. It was used in the preparation of 2-bromobenzoquinone.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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3,4-Dihydro-2H-pyran 97%

Sigma-Aldrich

D106208

3,4-Dihydro-2H-pyran

Hydroquinone ReagentPlus®, ≥99%

Sigma-Aldrich

H9003

Hydroquinone

T J Monks et al.
Molecular pharmacology, 34(1), 15-22 (1988-07-01)
The formation of potentially reactive thiols has been postulated to play a role in the nephrotoxicity caused by a number of glutathione and/or cysteine conjugates. However, the inherent reactivity of such compounds has precluded both their identification in biological systems
T J Monks et al.
Drug metabolism and disposition: the biological fate of chemicals, 13(5), 553-559 (1985-09-01)
Incubation of either o-bromophenol or 2-bromohydroquinone with rat liver microsomes and 0.25 mM 35S-glutathione (GSH) gave rise to several isomeric 35S-GSH conjugates. A mixture of these isomeric GSH conjugates was prepared chemically and two were purified by HPLC; 1H-NMR spectroscopy
R G Schnellmann
Toxicology and applied pharmacology, 99(1), 11-18 (1989-06-01)
2-Bromohydroquinone (BHQ) plays an important role in bromobenzene-induced nephrotoxicity and is a model toxic hydroquinone. Since BHQ has a quinone nucleus and various quinones have been shown to produce cytotoxicity via oxidative stress, the goal of this study was to
G W Miller et al.
Toxicology and applied pharmacology, 125(2), 192-197 (1994-04-01)
We have previously shown that strychnine mimics the cytoprotective properties of glycine in renal proximal tubule (RPT) suspensions exposed to antimycin A (AA). The aims of this study were to determine whether the cytoprotective properties of strychnine applied to various
S S Lau et al.
Biochemical and biophysical research communications, 152(1), 223-230 (1988-04-15)
2-Bromo-(diglutathion-Syl)hydroquinone (2-Br-[diGSyl]HQ) is a more potent nephrotoxicant than any of three mono-substituted isomers. The reason for this differential toxicity is unknown. We now report that the rate of uptake of 2-Br-(diGSyl)HQ, 2-Br-3-(GSyl)HQ, 2-Br-5-(GSyl)-HQ and 2-Br-6(GSyl)HQ by kidney slices was 2.4
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