123072

Luminol

97%

• Sinónimos: 3-Aminophthalhydrazide, 5-Amino-2,3-dihydro-1,4-phthalazinedione
• Fórmula empírica (notación de Hill): C₈H₇N₃O₂
• Número de CAS: 521-31-3
• Peso molecular: 177.16
• Beilstein/REAXYS Number: 383929
• EC Number: 208-309-4
• MDL number: MFCD00006890
• UNSPSC Code: 12352103
• PubChem Substance ID: 24847519
• NACRES: NA.23

Propiedades

• assay: 97%
• mp: >300 °C (lit.)
• SMILES string: Nc1cccc2C(=O)NNC(=O)c12
• InChI: 1S/C8H7N3O2/c9-5-3-1-2-4-6(5)8(13)11-10-7(4)12/h1-3H,9H2,(H,10,12)(H,11,13)
• InChI key: HWYHZTIRURJOHG-UHFFFAOYSA-N

Descripción

General description

Luminol is a very efficient and commonly used chemiluminiscent compound in condensed phase. When basic solutions of luminol containing oxygen are treated with an oxidizing agent, light is produced. Oxidising agents capable of initiating this particular reaction are Nitrogen dioxide, PAN, hydrogen peroxide, ozone and other atmospheric oxidants.

Application

• As a chemiluminiscent substance. Used to measure opsonic and phagocytic function.
• As a biological sensor. Used to detect the polymorphonuclear leukocytes (PMNL) response in a patient with a myeloperoxidase (MPO) deficiency.
• Used as a forensic test for blood.

Luminol has been used in a protocol to study the immune-related responses in Arabidopsis thaliana via luminol/peroxidase-based assay.

Features and Benefits

• Very effective chemiluminiscent compound.
• Can detect sub-part per billion levels of metal ions with simple and inexpensive instrumentation.

Used for chemiluminescence analysis of, for example, metal cations, blood, and glucococorticoids.

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves