113727
Norphenylephrine hydrochloride
98%
Sinónimos:
α-Aminomethyl-3-hydroxybenzyl alcohol hydrochloride, 3,α-Dihydroxyphenethylamine hydrochloride, Norfenefrine hydrochloride
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About This Item
Productos recomendados
Quality Level
assay
98%
form
solid
mp
162-164 °C (lit.)
functional group
amine
hydroxyl
SMILES string
Cl.NCC(O)c1cccc(O)c1
InChI
1S/C8H11NO2.ClH/c9-5-8(11)6-2-1-3-7(10)4-6;/h1-4,8,10-11H,5,9H2;1H
InChI key
OWMFSWZUAWKDRR-UHFFFAOYSA-N
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Application
Norphenylephrine hydrochloride was used in the study of the effects of phenylephrine on the isolated heart of rabbit.
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1. In the driven rabbit left atrium alpha-adrenoceptors mediate the inotropic effect of phenylephrine and the prolongation of functional refractory period by sympathomimetic amines.2. These receptors are highly sensitive to blockade by phentolamine and phenoxybenzamine.3. Prolongation of functional refractory period
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Chromatograms
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